PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains.
PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains.
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Pepcyber:P〜PEP:由磷蛋白结合结构域介导的人类蛋白质相互作用的数据库。
DOI:
10.1093/nar/gkm854
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Li, Tongbin
中科院分区:
文献类型:
--
作者:
Gong, Wuming;Zhou, Dihan;Ren, Yongliang;Wang, Yejun;Zuo, Zhixiang;Shen, Yanping;Xiao, Feifei;Zhu, Qi;Hong, Ailing;Zhou, Xiaochuan;Gao, Xiaolian;Li, Tongbin
Phosphoprotein-binding domains (PPBDs) mediate many important cellular and molecular processes. Ten PPBDs have been known to exist in the human proteome, namely, 14-3-3, BRCT, C2, FHA, MH2, PBD, PTB, SH2, WD-40 and WW. PepCyber:P∼PEP is a newly constructed database specialized in documenting human PPBD-containing proteins and PPBD-mediated interactions. Our motivation is to provide the research community with a rich information source emphasizing the reported, experimentally validated data for specific PPBD–PPEP interactions. This information is not only useful for designing, comparing and validating the relevant experiments, but it also serves as a knowledge-base for computationally constructing systems signaling pathways and networks. PepCyber:P∼PEP is accessible through the URL, http://www.pepcyber.org/PPEP/. The current release of the database contains 7044 PPBD-mediated interactions involving 337 PPBD-containing proteins and 1123 substrate proteins.
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影响因子:
14.9
作者:
Obenauer, JC;Cantley, LC;Yaffe, MB
通讯作者:
Yaffe, MB
影响因子:
14.9
作者:
Ceol, Arnaud;Chatr-aryamontri, Andrew;Cesareni, Gianni
通讯作者:
Cesareni, Gianni
影响因子:
16
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Durocher, D;Taylor, IA;Yaffe, MB
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Yaffe, MB
影响因子:
16
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通讯作者:
Shi, YG
影响因子:
46.9
作者:
Hermjakob, H;Montecchi-Palazzi, L;Apweiler, R
通讯作者:
Apweiler, R