Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand.
Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand.
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DOI：
10.3390/ijerph15061163
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发表时间：
2018-06-03
影响因子：
--
通讯作者：
Woskie S
中科院分区：
文献类型：
--
作者：
Konthonbut P;Kongtip P;Nankongnab N;Tipayamongkholgul M;Yoosook W;Woskie S
这项研究旨在评估怀孕28周、分娩和产后2个月妇女尿液中以及新生儿胎粪中的百草枯浓度。总共有79名孕妇从位于泰国农业地区的三家医院招募。研究对象接受了有关个人特征、农业活动和农药使用模式的访谈。使用配备荧光检测器的高效液相色谱法分析了尿液和胎粪中的百草枯。妊娠28周、分娩和产后2个月尿中百草枯浓度的几何平均值（GSD）分别为2.04（4.22）、2.06（5.04）和2.42（5.33）纳克/毫升。农民和非农民在妊娠28周、分娩和产后2个月的尿百草枯浓度无显著差异（分别为p = 0.632、p = 0.915、p = 0.57）。胎粪中百草枯浓度的几何平均值为33.31（4.59）纳克/克。预测孕妇和新生儿接触百草枯的因素包括：在外工作、居住在农田附近、家庭成员在农场工作、饮用井水以及使用除草剂或百草枯。
This study aimed to assess paraquat concentrations in the urine of women at 28 weeks of pregnancy, delivery and 2 months postpartum and in the meconium of neonates. In all, 79 pregnant women were recruited from three hospitals located in agricultural areas in Thailand. The subjects were interviewed about personal characteristics, agricultural activities and pesticide use patterns. Paraquat was analyzed in urine and meconium using high performance liquid chromatography equipped with a fluorescence detector. The geometric mean (GSD) of urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum were 2.04 (4.22), 2.06 (5.04) and 2.42 (5.33) ng/mL, respectively. The urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum between agriculturist and non-agriculturist were not significantly different (p = 0.632, p = 0.915, p = 0.57, respectively). The geometric mean (GSD) of paraquat concentration in the meconium was 33.31 (4.59) ng/g. The factors predicting paraquat exposures among pregnant women and neonates included working outside, living near farmland, having family members who work on a farm, drinking well water and using herbicides or paraquat.
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影响因子：
4.7
作者：
Barlow, BK;Thiruchelvam, MJ;Richfield, EK
通讯作者：
Richfield, EK
影响因子：
3.8
作者：
Bartlett, Rachel M.;Murali, Dhanabalan;DeJesus, Onofre T.
通讯作者：
DeJesus, Onofre T.
DOI：
10.1080/10826079708005835
发表时间：
1997-01-01
影响因子：
1.3
作者：
Itagaki, T;Lai, SJ;Binder, SR
通讯作者：
Binder, SR
影响因子：
2
作者：
Ito, M;Hori, Y;Yoshioka, T
通讯作者：
Yoshioka, T
DOI：
10.1097/jom.0b013e318222f03a
发表时间：
2011-08
影响因子：
3.2
作者：
Coronado GD;Holte S;Vigoren E;Griffith WC;Barr DB;Faustman E;Thompson B
通讯作者：
Thompson B