Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.
Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.
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DOI：
10.1016/j.drugalcdep.2021.108595
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发表时间：
2021-04-01
影响因子：
4.2
通讯作者：
Gupta S
中科院分区：
文献类型：
--
作者：
Watson DP;Weathers T;McGuire A;Cohen A;Huynh P;Bowes C;O'Donnell D;Brucker K;Gupta S
近年来，已经开发了一些基于急诊科（艾德）的干预措施，为使用阿片类药物的人提供支持和/或治疗联系。然而，支持大多数这些干预措施的有效性的研究有限。POINT项目是一项基于ED的干预措施，旨在为阿片类药物过量幸存者提供纳洛酮和恢复支持，并将其与阿片类药物使用障碍（MOUD）的循证药物联系起来。对POINT进行了评价。完成了电子健康记录数据的差异中差异分析，以了解POINT工作人员工作时与不工作时收治到艾德的患者结局的差异。观察窗为2012年1月1日至2019年7月6日，其中包括N = 1462名独立个体，其中802名在POINT组中。重点结局包括分发的MOUD阿片类药物处方、分发的活性非MOUD阿片类药物处方、纳洛酮使用和药物中毒。POINT组的MOUD处方、非MOUD处方和纳洛酮使用率显著增加（所有p值< 0.001）。对随后的药物中毒相关住院没有显著影响。结果支持POINT正在实现其两个主要目标的说法，即增加纳洛酮的使用和将患者与MOUD联系起来。这些结果的推广是有限的，但是，评价有助于一个新兴的研究领域，可以为今后的工作奠定基础。
In recent years, a number of emergency department (ED)-based interventions have been developed to provide supports and/or treatment linkage for people who use opioids. However, there is limited research supporting the effectiveness of the majority of these interventions. Project POINT is an ED-based intervention aimed at providing opioid overdose survivors with naloxone and recovery supports and connecting them to evidence-based medications for opioid use disorder (MOUD). An evaluation of POINT was conducted. A difference-in-difference analysis of electronic health record data was completed to understand the difference in outcomes for patients admitted to the ED when a POINT staff member was working versus times when they were not. The observation window was January 1, 2012 to July 6, 2019, which included N = 1462 unique individuals, of which 802 were in the POINT arm. Outcomes of focus include MOUD opioid prescriptions dispensed, active non-MOUD opioid prescriptions dispensed, naloxone access, and drug poisonings. The POINT arm had a significant increase in MOUD prescriptions dispensed, non-MOUD prescriptions dispensed, and naloxone access (all p-values < 0.001). There was no significant effect related to subsequent drug poisoning-related hospital admissions. The results support the assertion that POINT is meeting its two primary goals related to increasing naloxone access and connecting patients to MOUD. Generalization of these results is limited; however, the evaluation contributes to a nascent area of research and can serve a foundation for future work.
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影响因子：
4.2
作者：
Masson, CL;Sorensen, JL;Perlman, DC
通讯作者：
Perlman, DC
影响因子：
4.4
作者：
Powell, Kristen Gilmore;Treitler, Peter;Hallcom, Donald
通讯作者：
Hallcom, Donald
影响因子：
2.9
作者：
Ambrose, Graham;Amlani, Ashraf;Buxton, Jane A.
通讯作者：
Buxton, Jane A.
影响因子：
4.4
作者：
Marlatt, GA
通讯作者：
Marlatt, GA
DOI：
10.1111/add.13900
发表时间：
2017-11
期刊：
Addiction (Abingdon, England)
影响因子：
--
作者：
Busch SH;Fiellin DA;Chawarski MC;Owens PH;Pantalon MV;Hawk K;Bernstein SL;O'Connor PG;D'Onofrio G
通讯作者：
D'Onofrio G