Germline stem cells: origin and destiny.
Germline stem cells: origin and destiny.
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DOI:
10.1016/j.stem.2012.05.016
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发表时间:
2012-06-14
期刊:
影响因子:
23.9
通讯作者:
Lehmann, Ruth
中科院分区:
文献类型:
--
作者:
Lehmann, Ruth
Germline stem cells are key to genome transmission to future generations. Over recent years, there have been numerous insights into the regulatory mechanisms that govern both germ cell specification and the maintenance of the germline in adults. Complex regulatory interactions with both the niche and the environment modulate germline stem cell function. This perspective highlights some examples of this regulation to illustrate the diversity and complexity of the mechanisms involved.
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