Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial.

Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial.
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DOI:
10.2196/43164
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发表时间:
2023-04-20
期刊:
影响因子:
5.2
通讯作者:
Thomas EB
Thomas EB
中科院分区:
医学2区
文献类型:
--
作者:
Cochran A;Maronge JM;Victory A;Hoel S;McInnis MG;Thomas EB

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移动的干预措施有望以其广泛的覆盖面和灵活的交付方式填补护理方面的空白。我们的目标是调查一个移动的版本的接受和承诺治疗(ACT)的个人与双相情感障碍(BP)的交付。BP患者(n=30)参加了一项为期6周的微随机试验。每天两次,参与者在应用程序中记录症状,并反复随机(或不随机)接受ACT干预。自我报告的行为和情绪被测量为用于向有价值的领域移动或远离困难情绪的能量,以及来自BP调查中情绪数字调查(digiBP)的抑郁d和躁狂m评分。参与者平均完成了66%的应用内评估。干预没有显著影响平均朝向能量或远离能量,但显著增加了平均躁狂评分m(P=.008)和抑郁评分d(P=.02)。这是由于烦躁不安和易怒的增加,干预措施侧重于提高对内部经验的认识。这项研究的结果不支持对BP患者的移动的ACT进行更大规模的研究,但对未来寻求BP患者移动的治疗的研究具有重要意义。ClinicalTrials.gov NCT 04098497; https://clinicaltrials.gov/ct2/show/NCT04098497
Mobile interventions promise to fill in gaps in care with their broad reach and flexible delivery. Our goal was to investigate delivery of a mobile version of acceptance and commitment therapy (ACT) for individuals with bipolar disorder (BP). Individuals with BP (n=30) participated in a 6-week microrandomized trial. Twice daily, participants logged symptoms in the app and were repeatedly randomized (or not) to receive an ACT intervention. Self-reported behavior and mood were measured as the energy devoted to moving toward valued domains or away from difficult emotions and with depressive d and manic m scores from the digital survey of mood in BP survey (digiBP). Participants completed an average of 66% of in-app assessments. Interventions did not significantly impact the average toward energy or away energy but did significantly increase the average manic score m (P=.008) and depressive score d (P=.02). This was driven by increased fidgeting and irritability and interventions focused on increasing awareness of internal experiences. The findings of the study do not support a larger study on the mobile ACT in BP but have significant implications for future studies seeking mobile therapy for individuals with BP. ClinicalTrials.gov NCT04098497; https://clinicaltrials.gov/ct2/show/NCT04098497
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