Predictive Factors of Prolonged Ventilation Following Cardiac Surgery with Cardiopulmonary Bypass.
Predictive Factors of Prolonged Ventilation Following Cardiac Surgery with Cardiopulmonary Bypass.
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DOI：
10.21470/1678-9741-2020-0164
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发表时间：
2021-12-03
影响因子：
1.3
通讯作者：
Rabus MB
中科院分区：
文献类型：
--
作者：
Aksoy R;Karakoc AZ;Cevirme D;Elibol A;Yigit F;Yilmaz Ü;Rabus MB
在这项试验中，我们首先旨在研究在我们中心进行的体外循环（CPB）心脏手术后延长机械通气（PMV）的主要预测因素，其次，我们试图找出独立因素对死亡率的影响。回顾性研究了2017年7月至2018年8月期间接受CPB心脏手术的207例患者。根据呼吸机依赖持续时间将患者随机分为两个亚组（组1 <24小时，n=164，79%;组2 >24小时，n=43，21%）。本研究入组了207例接受CPB心脏手术的患者（平均年龄59.47±10.56岁）（n=145，70%的男性患者; n=62，30%的女性患者）。在这些患者中，43例（n=43，20.77%）插管时间延长。经多因素Logistic回归分析，术前性别、性别、年龄、性别、性别、年龄、性别、（OR=2.321，P=0.028），白细胞增多（OR=1.233，P=0.006），围手术期乳酸水平CPB时间（OR = 1.012，P = 0.012）和术后因出血翻修（OR=23.125，P=0.040）。结果表明，PMV对住院死亡率无影响（OR=1.979，P=0.420）。在我们的报告中，我们发现，不同于以往的研究，术中乳酸水平，表现器官灌注和氧合被包括在内，并在早期拔管组相比，PMV组有显着差异。女性、术前白细胞增多、术中CPB时间、乳酸水平和术后出血翻修是PMV的独立预测因素。此外，PMV并不影响住院期间的早期死亡率。
In this trial, we initially aimed to investigate the major predictive factors for prolonged mechanical ventilation (PMV) following cardiac surgery with cardiopulmonary bypass (CPB) in our center and, secondarily, we tried to find out the effects of the independent factors on mortality. Between July 2017 and August 2018, 207 patients who underwent cardiac surgery with CPB were retrospectively investigated. The patients were randomly divided into two subgroups according to the duration of ventilator dependence (group 1 <24 hours, n=164, 79%; group 2 >24 hours, n=43, 21%). 207 patients (mean age 59.47±10.56) who underwent cardiac surgery with CPB were enrolled in this study (n=145, 70% of male patients; n=62, 30% of female patients). Amid these patients, 43 (n=43, 20.77%) had prolonged intubation time. After multivariate logistic regression analysis among preoperative factors, female gender (OR=2.321, P=0.028), leukocytosis (OR=1.233, P=0.006), perioperative lactate level (OR=1.224, P=0.027), CPB time (OR=1.012, P=0.012) and postoperative revision for bleeding (OR=23.125, P=0.040) were significantly detected. The effect of predictive factors on mortality after cardiac surgery was determined and found that PMV did not affect hospital mortality (OR=1.979, P=0.420). In our report, we revealed, differently from previous studies, that intraoperative lactate levels which manifest organ perfusion and oxygenation were included and were significantly different in the early extubation group compared to the PMV group. Female gender, preoperative leukocytosis, intraoperative CPB time, lactate levels and postoperative revision for bleeding were the independent predictive factors for PMV. Moreover, PMV did not affect the early-term mortality during hospital stay.
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影响因子：
2.5
作者：
He, Siyi;Wu, Fan;Zhang, Jinbao
通讯作者：
Zhang, Jinbao
影响因子：
1.1
作者：
Totonchi Z;Baazm F;Chitsazan M;Seifi S;Chitsazan M
通讯作者：
Chitsazan M
影响因子：
9.6
作者：
KOLLEF, MH;WRAGGE, T;PASQUE, C
通讯作者：
PASQUE, C
DOI：
10.1016/j.jtcvs.2016.08.020
发表时间：
2017-01-01
影响因子：
6
作者：
Sharma, Vivek;Rao, Vivek;Wasowicz, Marcin
通讯作者：
Wasowicz, Marcin
影响因子：
4.6
作者：
Jacobs, Jeffrey P.;He, Xia;Shahian, David M.
通讯作者：
Shahian, David M.