Perinatal outcomes associated with assisted reproductive technology: the Massachusetts Outcomes Study of Assisted Reproductive Technologies (MOSART).
Perinatal outcomes associated with assisted reproductive technology: the Massachusetts Outcomes Study of Assisted Reproductive Technologies (MOSART).
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DOI：
10.1016/j.fertnstert.2014.12.119
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发表时间：
2015-04
影响因子：
6.7
通讯作者：
Hornstein, Mark D.
中科院分区：
文献类型：
--
作者：
Declercq, Eugene;Luke, Barbara;Belanoff, Candice;Cabral, Howard;Diop, Hafsatou;Gopal, Daksha;Hoang, Lan;Kotelchuck, Milton;Stern, Judy E.;Hornstein, Mark D.
以人口为基础，比较接受辅助生殖技术（ART）治疗的妇女、生育能力低下但未接受ART治疗的妇女和有生育能力的妇女的生育结果。对2004年7月1日至2008年12月31日期间在马萨诸塞州一家医院分娩的马萨诸塞州母亲的334,628例分娩和胎儿死亡进行纵向队列研究，并将其细分为三个亚组进行比较：ART组11,271例，欠生育6609例和可生育316,748例。四种结局：早产、低出生体重、小胎龄和围产期死亡，分别对单胎和双胞胎进行了logistic回归建模，主要比较了ART分娩和新创建的基于人口的亚组生育指标为低生育能力但未进行ART的妇女的分娩。单胎：ART组早产和低出生体重的风险（AOR分别为1.23和1.26）高于亚生育组，ART组和亚生育组的风险均高于可生育组。双胞胎：ART出生的围产期死亡风险显著低于生育（AOR 0.55）或欠生育（AOR 0.15）出生。使用以人口为基础的未接受抗逆转录病毒治疗的低生育能力新生儿的对照组显示，接受抗逆转录病毒治疗的单胎新生儿的早产和低出生体重率明显更高，但这些差异小于接受抗逆转录病毒治疗和可生育的新生儿之间的差异。有必要进一步完善低生育能力的测量和检查低生育能力的独立风险。
To compare on a population basis the birth outcomes of women treated with Assisted Reproductive Technologies (ART), women with indicators of subfertility but without ART, and fertile women. Longitudinal cohort study Massachusetts 334,628 births and fetal deaths to Massachusetts mothers giving birth in a Massachusetts hospital between July 1, 2004-December 31, 2008, subdivided into three subgroups for comparison: ART 11,271, subfertile 6,609, and fertile 316,748. None Four outcomes: preterm birth, low birthweight, small for gestational age and perinatal death, were modeled separately for singletons and twins using logistic regression with the primary comparison between ART births and those to the newly created population based subgroup of births to women with indicators of subfertility but no ART. Singletons: The risks for both preterm birth and low birthweight were higher for the ART group (AOR 1.23 and 1.26, respectively) compared to the subfertile group and risks in both the ART and subfertile groups were higher than those among fertile births. Twins: the risk of perinatal death was significantly lower among ART births than fertile (AOR 0.55) or subfertile (AOR 0.15) births. The use of a population based comparison group of subfertile births without ART demonstrated significantly higher rates of preterm birth and low birthweight in ART singleton births, but these differences are smaller than differences between ART and fertile births. Further refinement of the measurement of subfertile births and examination of the independent risks of subfertile births is warranted.
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影响因子：
7.2
作者：
Declercq, Eugene;Barger, Mary;Heffner, Linda J.
通讯作者：
Heffner, Linda J.
影响因子：
7.2
作者：
Jackson, RA;Gibson, KA;Croughan, MS
通讯作者：
Croughan, MS
影响因子：
2.3
作者：
Chow, JS;Benson, CB;Ginsburg, E
通讯作者：
Ginsburg, E
DOI：
10.1016/s0002-9378(98)70125-5
发表时间：
1998-11-01
影响因子：
9.8
作者：
Fitzsimmons, BP;Bebbington, MW;Fluker, MR
通讯作者：
Fluker, MR
影响因子：
9.8
作者：
Gaudoin, M;Dobbie, R;Fleming, R
通讯作者：
Fleming, R