Dentate transport discs can be used to reconstruct large segmental mandibular defects.
Dentate transport discs can be used to reconstruct large segmental mandibular defects.
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DOI：
10.1016/j.joms.2014.12.002
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发表时间：
2015-04
期刊：
影响因子：
--
通讯作者：
Opperman LA
中科院分区：
文献类型：
--
作者：
Elsalanty ME;Malavia V;Zakhary I;Mulone T;Kontogiorgos ED;Dechow PC;Opperman LA
本研究使用一种新型曲面重建钢板，测试齿状运输节段用于修复犬下颌骨前段大的U形缺损。比较有齿和无牙运输节段形成的骨再生的质量和数量。在5只成年猎狐犬上，切除右侧和左侧第4前磨牙前侧的下颌骨，造成70~75 mm的下颌骨缺损。重建采用三焦牵引成骨技术，使用骨运输重建钢板(BTRP02™)，同时激活两个运输单元，一个位于缺损区两侧，一个为有齿的，一个为无牙的。双侧牵张以1 mm/d的速度进行，直到节段在中线相互对接。经过39-44天的巩固后，动物被安乐死。应用显微计算机断层扫描技术对两侧骨再生的数量和质量进行比较。缺损区重建成功。两侧运输节段所形成的骨的数量和质量相似。两种运输节段形成的再生骨的骨体积分数和密度无明显差异。在远端节段，新生骨的骨体积分数和密度明显低于宿主骨，这可能是由于骨固化期较短所致。骨运输仍然是重建下颌骨前段缺损的一个可行的选择。使用有齿或无齿运输节段进行重建为外科医生提供了选择，这些患者往往需要进行这些手术。
This study tests the use of a dentate transport segment for the reconstruction of a large U-shaped defect in the anterior segment of the canine mandible, using a novel curved reconstruction plate. The quality and quantity of bone regenerate formed by dentate versus edentulous transport segments was compared. In five adult foxhound dogs, a defect of 70–75 mm was created in the canine mandible by excising the mandible anterior to the right and left 4th premolars. Reconstruction was done by trifocal distraction osteogenesis using a bone transport reconstruction plate (BTRP-02™), with two transport units being activated simultaneously, one on either side of the defect, one dentate and one edentulous. Bilateral distraction proceeded at a rate of 1mm/day until the segments docked against each other in midline. After 39–44 days consolidation, the animals were euthanized. The quantity and quality of bone regeneration on both sides were compared using micro-computed tomography. The defect reconstruction was successful. The amount and quality of bone formed by the transport segments was similar on both sides. There were no significant differences in the bone volume fraction and density of the regenerate bone formed by the two transport segments. The bone volume fraction and density of the regenerate was significantly lower than that of the host bone in the distal segments, likely due to the short consolidation period. Bone transport remains a viable option in reconstructing anterior segmental defects in the mandible. The use of either dentate or edentulous transport segments for reconstruction provides options for the surgeon in often highly compromised patients requiring these surgeries.
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影响因子：
0.9
作者：
Agabiti, Ivo;Cappare, Paolo;Crespi, Roberto
通讯作者：
Crespi, Roberto
影响因子：
3.4
作者：
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影响因子：
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作者：
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DOI：
10.1016/j.ajodo.2004.01.022
发表时间：
2005-05-01
影响因子：
3
作者：
Iseri, H;Kisnisci, R;Tüz, H
通讯作者：
Tüz, H
DOI：
10.5435/00124635-200401000-00005
发表时间：
2004-01-01
影响因子：
3.2
作者：
DeCoster, TA;Gehlert, R;Pirela-Cruz, MA
通讯作者：
Pirela-Cruz, MA