Functional genomic analysis of Hawaii marine metagenomes
Functional genomic analysis of Hawaii marine metagenomes
复制标题
夏威夷海洋宏基因组的功能基因组分析
DOI：
10.1007/s11434-014-0658-y
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发表时间：
2015-01
期刊：
影响因子：
18.9
通讯作者：
Huaiqiu Zhu
中科院分区：
文献类型：
--
作者：
Luying Liu;Jiangtao Guo;Jinxian Yao;Huaiqiu Zhu
Using high-throughput sequencing on metagenome to analyze marine microbial community, it is one of current main issues in the field of environmental microbe research. In this paper, we conducted the functional analysis on seven samples of metagenomic data from different depth seawater in Hawaii. The results of gene prediction and function annotation indicate that there are large amounts of potential novel genes of which functions remain unknown at present. Based on the gene annotation, codon usage bias is studied on ribosomal protein-related genes and shows an evident influence by the marine extreme environment. Furthermore, focusing on the marine environmental differences such as light intensity, dissolved oxygen, temperature and pressure among various depths, comparative analysis is carried out on related genes and metabolic pathways. Thus, the understanding as well as new insights into the correlation between marine environment and microbes are proposed at molecular level. Therefore, the studies herein afford a clue to reveal the special living strategies of microbial community from sea surface to deep sea.摘要对宏基因组高通量测序数据的分析, 是当前研究海洋微生物的重要方法。作者对夏威夷海域不同深度海水的微生物群落宏基因组进行功能基因组学分析。通过基因功能注释, 发现了大量潜在的新基因, 结果也表明极端环境加强了微生物密码子使用偏好。进一步根据光强、氧含量和低温高压等环境因素, 进行代谢通路和基因序列分析, 从分子水平上对海洋微生物与环境的关联和适应性提出若干新的认识, 探讨不同深度海洋环境中微生物特有的生存机制。
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影响因子：
4.1
作者：
Noguchi, Hideki;Taniguchi, Takeaki;Itoh, Takehiko
通讯作者：
Itoh, Takehiko
影响因子：
4.3
作者：
Kos, Peter B.;Deak, Zsuzsanna;Vass, Imre
通讯作者：
Vass, Imre
DOI：
10.1007/s004380051153
发表时间：
1999-12
期刊：
Molecular and General Genetics MGG
影响因子：
--
作者：
B. Wackwitz;J. Bongaerts;S. Goodman;G. Unden
通讯作者：
B. Wackwitz;J. Bongaerts;S. Goodman;G. Unden
影响因子：
5.4
作者：
Kennedy J;Flemer B;Jackson SA;Lejon DP;Morrissey JP;O'Gara F;Dobson AD
通讯作者：
Dobson AD
深地中海的宏基因组学，一种温暖的男性气概栖息地。
影响因子：
3.7
作者：
Martin-Cuadrado, Ana-Belen;Lopez-Garcia, Purificacion;Alba, Juan-Carlos;Moreira, David;Monticelli, Luis;Strittmatter, Axel;Gottschalk, Gerhard;Rodriguez-Valera, Francisco
通讯作者：
Rodriguez-Valera, Francisco