An innovative, non-invasive sensation meter allows for a more comprehensive understanding of bladder sensation events: A prospective study in participants with normal bladder function.
An innovative, non-invasive sensation meter allows for a more comprehensive understanding of bladder sensation events: A prospective study in participants with normal bladder function.
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DOI：
10.1002/nau.23831
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发表时间：
2019-01
影响因子：
2
通讯作者：
Klausner AP
中科院分区：
文献类型：
--
作者：
Naimi HA;Nagle AS;Vinod NN;Kolli H;Sheen D;De Wachter SG;Speich JE;Klausner AP
目前在尿动力学实验室之外，还没有标准化的方法来表征膀胱充盈期间膀胱感觉的变化。本研究的目的是在膀胱功能正常的个体中使用感觉计在口服水化期间表征实时膀胱感觉事件。参加加速水合研究的参与者饮用2L Gatorade-G2®，并利用感觉计记录两个连续充盈-排空周期的实时膀胱感觉（0-100%）、言语感觉阈值和“紧张”、“压力”、“刺痛”、“疼痛”和“其他”的感觉描述符。获得了来自21名参与者（12名女性/9名男性）的数据，并证明了每次填充平均8-9次感觉事件（感觉的显著变化），感觉事件的总数和感觉事件之间的体积没有差异（填充1 vs填充2）。在容量较高的四分位数中，感觉事件的数量增加。“压力”和“刺痛”事件描述符是两种填充中最常用的描述符。创新的感觉计包括“紧张”、“刺痛”、“压力”和“疼痛”的感觉事件描述符，以实现对膀胱感觉的更全面理解以及对感觉事件的实时识别、量化和表征。该研究证明了每次填充8-9个事件，填充期间感觉加速，以及独特的感觉事件描述符模式。这项技术可能有助于识别与膀胱过度活动症（OAB）和衰老相关的新感觉模式。
There is currently no standardized method of characterizing changes in bladder sensation during bladder filling outside of the urodynamics laboratory. The purpose of this investigation was to characterize real-time bladder sensation events using a sensation meter during oral hydration in individuals with normal bladder function. Participants enrolled in an accelerated hydration study drank 2 L Gatorade-G2® and utilized a sensation meter to record real-time bladder sensation (0–100%), verbal sensory thresholds, and sensation descriptors of “tense,” “pressure,” “tingling,” “painful,” and “other” for two consecutive fill-void cycles. Data from 21 participants (12 females/9 males) were obtained and demonstrated an average of 8–9 sensation events (significant changes in sensation) per fill with no differences in the total number of sensation events and volume between sensation events (fill 1 vs fill 2). An increased number of sensation events occurred at higher capacity quartiles. Event descriptors of “pressure” and “tingling” were the most commonly chosen descriptors in both fills. The innovative sensation meter includes the sensation event descriptors of “tense,” “tingling,” “pressure,” and “painful,” to enable a more comprehensive understanding of bladder sensation as well as real-time identification, quantification, and characterization of sensation events. The study demonstrates 8–9 events per fill, acceleration of sensation during filling, and unique sensation event descriptor patterns. This technology may be helpful in the identification of novel sensation patterns associated with overactive bladder (OAB) and aging.
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影响因子：
2
作者：
Heeringa, R.;van Koeveringe, G. A.;de Wachter, S. G. G.
通讯作者：
de Wachter, S. G. G.
影响因子：
2
作者：
De Wachter, S;De Laet, K;Wyndaele, JJ
通讯作者：
Wyndaele, JJ
DOI：
10.1111/j.1464-410x.1994.tb07512.x
发表时间：
1994-03-01
期刊：
BRITISH JOURNAL OF UROLOGY
影响因子：
--
作者：
ROBERTSON, AS;GRIFFITHS, CJ;NEAL, DE
通讯作者：
NEAL, DE
影响因子：
2.1
作者：
Coyne, Karin S.;Sexton, Chris C.;Milsom, Ian
通讯作者：
Milsom, Ian
影响因子：
2
作者：
Nagle AS;Speich JE;De Wachter SG;Ghamarian PP;Le DM;Colhoun AF;Ratz PH;Barbee RW;Klausner AP
通讯作者：
Klausner AP