Changes in Bone Mineral Density of the Femur and Tibia Before Injury to 2 Years After Anterior Cruciate Ligament Reconstruction in Division I Collegiate Athletes.
Changes in Bone Mineral Density of the Femur and Tibia Before Injury to 2 Years After Anterior Cruciate Ligament Reconstruction in Division I Collegiate Athletes.
复制标题
I组大学生运动员前交叉韧带重建术后2年损伤前股骨和胫骨骨密度的变化。
DOI：
10.1177/03635465221099456
复制
发表时间：
2022-07
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
Osteoarthritis (OA) is a significant long-term concern following anterior cruciate ligament reconstruction (ACLR). Low bone mineral density (BMD), particularly of the subchondral region, has been associated with the development of OA and is evident at the knee in individuals long after ACLR. It is unknown if persistent BMD deficits are present in high-level collegiate athletes. Evaluate bilateral changes in BMD of the femur and tibia from preinjury to 24 months post-ACLR in collegiate athletes. We hypothesized that BMD of both the distal femur and proximal tibia would be significantly reduced within the surgical limb initially post-operatively, but return to preinjury levels by 24 months post-ACLR. Analysis of routinely collected athletic performance data; Level of Evidence, 3. Thirty-three Division I collegiate athletes were identified between 2010 and 2021 (13 female) who had total body dual-energy x-ray absorptiometry (DXA) scans acquired prior to sustaining an ACL injury. DXA scans were repeated at 6, 12, and 24 months (6M, 12M, 24M) post-ACLR. Linear mixed effects models assessed differences in BMD of 5%, 15%, and 50% of femur length (F5, F15, F50) and 5%, 15%, and 50% of tibia length (T5, T15, T50) between post-ACLR time-points and preinjury within each limb, reported as Tukey-adjusted p-values. Compared to preinjury, BMD at F5 of the surgical limb was reduced 0.15 (0.02) g/cm2 at 6M (p-value < 0.001). BMD at F15 of the surgical limb was reduced 0.06 (0.01), 0.09 (0.01), 0.09 (0.01) g/cm2 at 6M, 12M, and 24M, respectively (all p-values < 0.001). BMD at T5 of the non-surgical limb was reduced 0.07 (0.02) g/cm2 at 12M (p-value = 0.02) and 0.10 (0.02) g/cm2 at 24M (p-value = 0.001). BMD at T15 of the surgical limb was reduced 0.07 (0.01) g/cm2 at 6M and 0.08 (0.02) g/cm2 at 12M (p-values < 0.001). BMD deficits of the surgical limb F15 region persisted out to 24M (−7.1%) post-ACLR compared to preinjury in collegiate athletes. The surgical limb F5 and T15 regions BMD were reduced at 6M and 12M, but not at 24M compared to preinjury levels. For the non-surgical limb, no significant differences were detected except for the T5 region at 12M (−5.1%) and 24M (−7.2%). The BMD at the F50 and T50 regions of both limbs were not significantly different than preinjury levels at any time post-ACLR. Following ACLR, long-term deficits in femoral BMD may be related to the early onset and progression of OA and should be further explored.
登录
查看更多内容
影响因子：
2.4
作者：
Duda, GN;Schneider, E;Chao, EYS
通讯作者：
Chao, EYS
影响因子：
4.2
作者：
Leppälä, J;Kannus, P;Järvinen, M
通讯作者：
Järvinen, M
影响因子：
4.9
作者：
Barr AJ;Campbell TM;Hopkinson D;Kingsbury SR;Bowes MA;Conaghan PG
通讯作者：
Conaghan PG
影响因子：
168.9
作者：
Kanis, JA
通讯作者：
Kanis, JA
影响因子：
3.8
作者：
Claes, Steven;Hermie, Laurens;Verdonk, Peter
通讯作者：
Verdonk, Peter