Understanding Silicon Nitride’s Biological Properties: From Inert to Bioactive Ceramic
Understanding Silicon Nitride’s Biological Properties: From Inert to Bioactive Ceramic
复制标题
了解氮化硅的生物特性：从惰性陶瓷到生物活性陶瓷
DOI：
10.4028/www.scientific.net/kem.782.289
复制
发表时间：
2018
期刊：
影响因子：
--
通讯作者：
G. Pezzotti
中科院分区：
文献类型：
--
作者：
E. Marin;A. Rondinella;F. Boschetto;M. Zanocco;B. McEntire;B. Bal;G. Pezzotti
由于机械强度和断裂韧性的有利组合，氮化硅已被用作承载生物陶瓷，特别是用于脊柱融合手术中使用的植入物。直到最近才观察到，氮化硅的所谓惰性表面实际上是生物活性的：氮和氧之间的缓慢但不可忽略的pH控制的离子交换导致草酸和氨基团的形成和洗脱，也导致有效保护免受细菌定植。这些性能可以通过化学和机械处理进一步调节。
Due to the favourable combination of mechanical strength and fracture toughness, silicon nitride has been applied as a load-bearing bioceramic, in particular for implants used in spinal fusion surgery. Only recently it has been observed that the supposedly inert surface of silicon nitride is actually bioactive: a slow, but not negligible, pH controlled, ionic exchange between nitrogen and oxygen leads to the formation and elution of silicic acid and ammonia groups, also resulting in an effective protection against bacteria colonization. These properties could be further modulated by chemical and mechanical treatments.
影响因子：
9.7
作者：
Bock, Ryan M.;McEntire, Bryan J.;Pezzotti, Giuseppe
通讯作者：
Pezzotti, Giuseppe