Understanding and manipulating plant lipid composition: Metabolic engineering leads the way.
Understanding and manipulating plant lipid composition: Metabolic engineering leads the way.
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DOI：
10.1016/j.pbi.2014.04.001
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发表时间：
2014-06
影响因子：
9.5
通讯作者：
Cahoon EB
中科院分区：
文献类型：
--
作者：
Napier JA;Haslam RP;Beaudoin F;Cahoon EB
描述植物脂肪代谢的最新进展。描述植物代谢工程的突破性成果。对植物合成生物学实际应用的洞察。长期以来，控制植物种子油成分以提供适合饲料或燃料的强化脂肪酸成分一直是代谢工程师的目标。最近，我们对不同关键代谢池(如磷脂酰胆碱和二酰甘油)的酰基变化流量的了解取得了进展，这使得我们能够进行更有针对性的干预。当以迭代的方式与进一步的脂肪组学分析相结合时，我们用新油生产植物的能力已经取得了重大突破。总体而言，这些研究工作在代谢工程和合成生物学之间，展示了此类研究产生的积极的基础和应用成果。
Description of recent advances in plant lipid metabolism. Description of break-through achievements in plant metabolic engineering. Insights into the practical applications of plant synthetic biology. The manipulation of plant seed oil composition so as to deliver enhanced fatty acid compositions suitable for feed or fuel has long been a goal of metabolic engineers. Recent advances in our understanding of the flux of acyl-changes through different key metabolic pools such as phosphatidylcholine and diacylglycerol have allowed for more targeted interventions. When combined in iterative fashion with further lipidomic analyses, significant breakthroughs in our capacity to generate plants with novel oils have been achieved. Collectively these studies, working at the interface between metabolic engineering and synthetic biology, demonstrate the positive fundamental and applied outcomes derived from such research.
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影响因子：
13.8
作者：
Burgal J;Shockey J;Lu C;Dyer J;Larson T;Graham I;Browse J
通讯作者：
Browse J
影响因子：
7.4
作者：
Horn, Patrick J.;James, Christopher N.;Chapman, Kent D.
通讯作者：
Chapman, Kent D.
影响因子：
7.2
作者：
Horn, Patrick J.;Silva, Jillian E.;Chapman, Kent D.
通讯作者：
Chapman, Kent D.
影响因子：
4.8
作者：
Hoffmann, Mareike;Wagner, Martin;Feussner, Ivo
通讯作者：
Feussner, Ivo
影响因子：
5.1
作者：
Petrie JR;Shrestha P;Liu Q;Mansour MP;Wood CC;Zhou XR;Nichols PD;Green AG;Singh SP
通讯作者：
Singh SP