Neural mechanisms of interference control in working memory: effects of interference expectancy and fluid intelligence.
Neural mechanisms of interference control in working memory: effects of interference expectancy and fluid intelligence.
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DOI：
10.1371/journal.pone.0012861
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发表时间：
2010-09-20
期刊：
影响因子：
3.7
通讯作者：
Braver TS
中科院分区：
文献类型：
--
作者：
Burgess GC;Braver TS
行政控制的一个关键方面是限制干扰的不利影响的能力。先前的研究表明，在干扰开始后，左腹外侧前额叶皮层被激活，这表明干扰可能以反应性的方式被解决。然而，我们建议干扰控制也可以以一种主动的方式来防止干扰的影响。目前的研究通过改变干扰预期和流体智力（gF）这两个因素来研究干扰控制的时间动态，这两个因素可能会影响干扰控制是主动还是被动地运作。使用了最近底片任务的修改版本。通过改变最近的消极（干扰）试验与最近的积极（促进）试验的比例，在任务块之间操纵干扰预期。此外，我们探讨了gF是否影响了利用特定干扰控制机制的倾向。当干扰预期较低时，外侧前额叶皮层的活动复制了先前的结果，显示出反应性控制模式（即在探测期间对干扰敏感）。相比之下，当干扰预期较高时，双侧前额叶皮层的激活更能表明主动控制机制（探测期之前的干扰相关效应）。另外，研究结果表明，高血糖个体的主动控制模式更为明显，而低血糖个体的反应性控制模式更为明显。结果表明，干预控制存在两种神经机制，其差异表达受实验（如期望效应）和个体差异（如gF）因素的调节。
A critical aspect of executive control is the ability to limit the adverse effects of interference. Previous studies have shown activation of left ventrolateral prefrontal cortex after the onset of interference, suggesting that interference may be resolved in a reactive manner. However, we suggest that interference control may also operate in a proactive manner to prevent effects of interference. The current study investigated the temporal dynamics of interference control by varying two factors – interference expectancy and fluid intelligence (gF) – that could influence whether interference control operates proactively versus reactively. A modified version of the recent negatives task was utilized. Interference expectancy was manipulated across task blocks by changing the proportion of recent negative (interference) trials versus recent positive (facilitation) trials. Furthermore, we explored whether gF affected the tendency to utilize specific interference control mechanisms. When interference expectancy was low, activity in lateral prefrontal cortex replicated prior results showing a reactive control pattern (i.e., interference-sensitivity during probe period). In contrast, when interference expectancy was high, bilateral prefrontal cortex activation was more indicative of proactive control mechanisms (interference-related effects prior to the probe period). Additional results suggested that the proactive control pattern was more evident in high gF individuals, whereas the reactive control pattern was more evident in low gF individuals. The results suggest the presence of two neural mechanisms of interference control, with the differential expression of these mechanisms modulated by both experimental (e.g., expectancy effects) and individual difference (e.g., gF) factors.
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DOI：
10.1037/0278-7393.32.2.183
发表时间：
2006-03-01
影响因子：
2.6
作者：
Bunting, M
通讯作者：
Bunting, M
影响因子：
5.7
作者：
FRISTON, KJ;HOLMES, AP;TURNER, R
通讯作者：
TURNER, R
DOI：
10.3758/bf03204507
发表时间：
1993-05-01
期刊：
BEHAVIOR RESEARCH METHODS INSTRUMENTS & COMPUTERS
影响因子：
--
作者：
COHEN, J;MACWHINNEY, B;PROVOST, J
通讯作者：
PROVOST, J
影响因子：
3.3
作者：
Jonides, J;Nee, DE
通讯作者：
Nee, DE
影响因子：
4
作者：
Diamond, Adele
通讯作者：
Diamond, Adele