P300-like potential disappears in rabbits with lesions in the nucleus basalis of Meynert

P300-like potential disappears in rabbits with lesions in the nucleus basalis of Meynert
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Meynert 基底核损伤的家兔 P300 样电位消失

DOI:
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发表时间:
1997
影响因子:
2
通讯作者:
Kazuro Takahashi
Kazuro Takahashi
中科院分区:
医学4区
文献类型:
--
作者:
Yuping Wang;K. Nakashima;Y. Shiraishi;Y. Kawai;E. Ohama;Kazuro Takahashi

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Abstract The nucleus basalis of Meynert (nbM, substantia innominata) in the basal forebrain provides a single major source of cholinergic innervation for the entire cerebral cortex. We tested the effects of nbM lesions on rabbit P300-like potentials. The P300-like event-related potential (ERP) was recorded in 14 female adult white rabbits using a conventional auditory oddball paradigm. The probability of occurrence for the 2-kHz and 1-kHz stimulus tones was 90% (frequent) and 10% (rare), respectively. The nbM was destroyed bilaterally in seven rabbits referred to as the nbM (+) group. In the other seven rabbits [nbM (–) group], putamen nuclei (n=6) or amygdaloid nuclei (n=1) were destroyed bilaterally. The evoked responses were recorded before and 1 week after the destruction. In the nbM (+) group, P300 amplitude to rare stimuli significantly decreased after the lesion. In the nbM (–) group, no component of ERPs showed changes after the lesions. These results indicate that the nbM might be involved in the generation of the rabbit P300.
DOI: 10.1016/0168-5597(92)90018-7
发表时间: 1992-03
期刊: Electroencephalography and clinical neurophysiology
影响因子: --
作者:
S. Yamaguchi;R. Knight
通讯作者: S. Yamaguchi;R. Knight
DOI: 10.1126/science.6691145
发表时间: 1984-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
ARTHUR, DL;STARR, A
通讯作者: STARR, A
DOI: 10.1016/0013-4694(95)98475-n
发表时间: 1995-04-01
期刊: ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子: --
作者:
HALGREN, E;BAUDENA, P;BIRABEN, A
通讯作者: BIRABEN, A
DOI: 10.1016/0013-4694(91)90018-y
发表时间: 1991
期刊: Electroencephalography and clinical neurophysiology
影响因子: --
作者:
S. Yamaguchi;R. Knight
通讯作者: S. Yamaguchi;R. Knight
“Cat P300”在间隔损伤后消失。
DOI: 10.1016/0013-4694(88)90035-1
发表时间: 1988
期刊: Electroencephalography and clinical neurophysiology
影响因子: --
作者:
Harrison,JB;Buchwald,JS;Kaga,K;Woolf,NJ;Butcher,LL
通讯作者: Butcher,LL