How large is the periablational zone after radiofrequency and microwave ablation? Computer-based comparative study of two currently used clinical devices.
How large is the periablational zone after radiofrequency and microwave ablation? Computer-based comparative study of two currently used clinical devices.
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DOI：
10.1080/02656736.2020.1823022
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Berjano E
中科院分区：
文献类型：
--
作者：
Trujillo M;Prakash P;Faridi P;Radosevic A;Curto S;Burdio F;Berjano E
旨在比较临床上分别用于射频（RFA）和微波消融（MWA）的两种市售器械形成的凝固（CZ）和消融周围（PZ）区的大小。使用计算机模型模拟使用3 cm Cool-tip施加器的RFA和使用Amica-Gen施加器的MWA。采用Arrhenius模型计算损伤指数（Ω）。当Ω> 4.6（>99%的受损细胞）时考虑CZ。具有0.6<Ω< 2.1的区域被认为是PZ（已经经历中度亚烧蚀高温的组织）。PZ体积与CZ体积的比率（PZ/CZ）被认为是性能的量度，因为低值意味着在保持PZ小的同时实现大的CZ。10分钟RFA（51 W）产生的消融周围区小于10分钟MWA（60和100 W MWA分别为11.3 cm 3和17.2和22.9 cm 3）。将持续时间从5分钟延长至10分钟，MWA中PZ的增加大于RFA（RFA为2.7 cm 3，60-100 W MWA为8.3-11.9 cm 3）。无论消融时间如何，RFA的PZ/CZ相对较高（65-69%），而MWA的PZ/CZ高度依赖于持续时间（5 - 10分钟之间增加高达25%）和施加的功率（随着功率增加，数值较小，60 W为102%，100 W为81%，均持续10分钟）。所有设置中的最低PZ/CZ为56%，采用100 W-5 min MWA获得。尽管RFA产生的消融周围区比MWA小，但100 W-5 min MWA提供的PZ/CZ最低。
To compare the size of the coagulation (CZ) and periablational (PZ) zones created with two commercially available devices in clinical use for radiofrequency (RFA) and microwave ablation (MWA), respectively. Computer models were used to simulate RFA with a 3-cm Cool-tip applicator and MWA with an Amica-Gen applicator. The Arrhenius model was used to compute the damage index (Ω). CZ was considered when Ω> 4.6 (>99% of damaged cells). Regions with 0.6<Ω< 2.1 were considered as the PZ (tissue that has undergone moderate sub-ablative hyperthermia). The ratio of PZ volume to CZ volume (PZ/CZ) was regarded as a measure of performance, since a low value implies achieving a large CZ while keeping the PZ small. Ten-min RFA (51 W) created smaller periablational zones than 10-min MWA (11.3 cm3 vs. 17.2 22.9 cm3, for 60 100 W MWA, respectively). Prolonging duration from 5 to 10 min increased the PZ in MWA more than in RFA (2.7 cm3 for RFA vs. 8.3–11.9 cm3 for 60–100 W MWA, respectively). PZ/CZ for RFA were relatively high (65–69%), regardless of ablation time, while those for MWA were highly dependent on the duration (increase of up to 25% between 5 and 10 min) and on the applied power (smaller values as power was raised, 102% for 60 W vs. 81% for 100 W, both for 10 min). The lowest PZ/CZ across all settings was 56%, obtained with 100 W-5 min MWA. Although RFA creates smaller periablational zones than MWA, 100 W-5 min MWA provides the lowest PZ/CZ.
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影响因子：
3.1
作者：
Amabile, Claudio;Ahmed, Muneeb;Goldberg, S. Nahum
通讯作者：
Goldberg, S. Nahum
影响因子：
5.8
作者：
Izzo, Francesco;Granata, Vincenza;Curley, Steven A.
通讯作者：
Curley, Steven A.
影响因子：
3.8
作者：
Bedoya, Mariajose;del Rio, Alejandro Munoz;Brace, Christopher L.
通讯作者：
Brace, Christopher L.
影响因子：
2.7
作者：
Irastorza, Ramiro M.;d'Avila, Andre;Berjano, Enrique
通讯作者：
Berjano, Enrique
DOI：
10.1016/j.ijheatmasstransfer.2006.11.045
发表时间：
2007-07-01
影响因子：
5.2
作者：
Abraham, J. P.;Sparrow, E. M.
通讯作者：
Sparrow, E. M.