Multidrug-Resistant Bacteria in the Community: An Update.
Multidrug-Resistant Bacteria in the Community: An Update.
复制标题
DOI：
10.1016/j.idc.2020.08.002
复制
发表时间：
2020-12
影响因子：
4.4
通讯作者：
Paterson DL
中科院分区：
文献类型：
--
作者：
van Duin D;Paterson DL
多重耐药（MDR）细菌是当前对公众健康最重要的威胁之一。通常，耐多药细菌与医院感染有关。然而，一些耐多药细菌已成为社区获得性感染的相当普遍的原因。这些可能是典型的社区获得性病原体，例如淋病奈瑟氏菌、志贺氏菌、沙门氏菌和肺炎链球菌。事实上，MDR 淋病奈瑟菌现在被 CDC 视为紧急威胁。耐多药细菌的社区传播（通常与医疗环境相关）也是一个重要的发展。耐甲氧西林金黄色葡萄球菌 (MRSA) 和产生超广谱 β-内酰胺酶 (ESBL) 的大肠杆菌是此类细菌中最常见的。这些疾病的流行是由社区中人与人之间的传播驱动的，对于产生 ESBL 的大肠杆菌来说，是由于农业中使用抗生素造成的。即将出现的一个重要的全球威胁是社区获得性高毒力肺炎克雷伯菌产生的碳青霉烯酶。此类菌株已在亚洲、欧洲和北美发现。防止耐多药细菌进一步社区传播至关重要，需要所有利益相关者采取多学科方法。
Multidrug resistant (MDR) bacteria are one of the most important current threats to public health. Typically, MDR bacteria are associated with nosocomial infections. However, some MDR bacteria have become quite prevalent causes of community-acquired infections. These may be pathogens which are classically community acquired such as Neisseria gonorrhoeae, Shigella, Salmonella and Streptococcus pneumoniae. Indeed, MDR N. gonorrhoeae is now regarded by the CDC as an urgent threat. The community spread of MDR bacteria, more typically associated with healthcare environments, is also a crucial development. Methicillin-resistant S. aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) producing E. coli are the most prevalent of such bacteria. The prevalence of these is driven by person to person transmission in the community and, in the case of ESBL producing E. coli by the use of antibiotics in agriculture. An important global threat on the horizon is represented by production of carbapenemases by community-acquired hypervirulent Klebsiella pneumoniae. Such strains have already been found in Asia, Europe and North America. Prevention of further community spread of MDR bacteria is of the utmost importance, and will require a multi-disciplinary approach involving all stakeholders.
登录
查看更多内容
影响因子：
168.9
作者：
DeLeo, Frank R.;Otto, Michael;Kreiswirth, Barry N.;Chambers, Henry F.
通讯作者：
Chambers, Henry F.
影响因子：
120.7
作者：
Epstein, Lauren;Hunter, Jennifer C.;Kallen, Alexander J.
通讯作者：
Kallen, Alexander J.
影响因子：
9.6
作者：
Davis, Joshua S.;McMillan, Mark;Anstey, Nicholas M.
通讯作者：
Anstey, Nicholas M.
影响因子：
7.5
作者：
Bruinsma, N;Stobberingh, E;van den Bogaard, A
通讯作者：
van den Bogaard, A
DOI：
10.1126/science.1220761
发表时间：
2012-08-31
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Forsberg KJ;Reyes A;Wang B;Selleck EM;Sommer MO;Dantas G
通讯作者：
Dantas G