Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report.

Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report.
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DOI:
10.1002/acn3.51508
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发表时间:
2022-03
影响因子:
5.3
通讯作者:
Trainer R
Trainer R
中科院分区:
医学2区
文献类型:
--
作者:
Gorgey AS;Sutor TW;Goldsmith JA;Ennasr AN;Lavis TD;Cifu DX;Trainer R

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一名C7完全性四肢瘫痪的男性参与了14周的体重支持跑步机训练(BWSTT)联合脊髓硬膜外刺激(SCES),4周无干预,以及2周以上的BWSTT + SCES。受试者表现出不稳定的静息坐位血压(BP; 131/66 mmHg)。回顾性分析后,静息收缩压降低,舒张压升高,得出安全的平均动脉压。每次BWSTT发作增加了五倍,体重支持百分比下降到69%。BWSTT + SCES安全有效地调节静息血压,减轻直立不耐受症状。这些效果在不训练4周后没有维持。
A male with C7 complete tetraplegia participated in 14 weeks of body weight supported treadmill training (BWSTT) combined with spinal cord epidural stimulation (SCES), 4 weeks of no intervention, and two more weeks of BWSTT + SCES. The participant presented with unstable resting seated blood pressure (BP; 131/66 mmHg). After retrospective analysis, resting systolic BP decreased and diastolic BP increased, yielding a safe mean arterial BP. There was a fivefold increase in BWSTT bouts per session, and percentage of body weight support decreased to 69%. BWSTT + SCES safely and effectively regulated resting BP and mitigated symptoms of orthostatic intolerance. These effects were not maintained after 4 weeks without training.
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