Body fatness, diabetes, physical activity and risk of kidney stones: a systematic review and meta-analysis of cohort studies.
Body fatness, diabetes, physical activity and risk of kidney stones: a systematic review and meta-analysis of cohort studies.
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DOI：
10.1007/s10654-018-0426-4
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发表时间：
2018-11
影响因子：
13.6
通讯作者：
Riboli E
中科院分区：
文献类型：
--
作者：
Aune D;Mahamat-Saleh Y;Norat T;Riboli E
我们进行了一项系统回顾和荟萃分析，以阐明肥胖、糖尿病和体力活动与肾结石风险之间的关系。检索了截至2018年4月22日的PubMed和Embase相关研究。使用随机效应模型计算总结相对风险（RR）和95%置信区间（CI）。纳入了13项队列研究。综合相对危险度为1.21（95% CI 1.12-1.30，I2 = 76%，n = 8）BMI每增加5个单位，1.16（95% CI 1.12-1.19，I2 = 0%，n = 5）腰围每增加10 cm，1.06（95% CI 1.04-1.08，I2 = 67%，n = 3）和1.12（95% CI 1.06-1.18，I2 = 86%，n = 3）。与非糖尿病受试者相比，糖尿病受试者的汇总RR为1.16（95% CI 1.03-1.31，I2 = 51%，n = 10），高体力活动与低体力活动的汇总RR为0.93（95% CI 0.78-1.10，I2 = 80%，n = 4）。这些结果表明肥胖和糖尿病以及肾结石风险之间存在正相关，但与体力活动无关。本文的在线版本（10.1007/s10654-018-0426-4）包含补充材料，可供授权用户使用。
We conducted a systematic review and meta-analysis to clarify the association between adiposity, diabetes, and physical activity and the risk of kidney stones. PubMed and Embase were searched up to April 22nd 2018 for relevant studies. Summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated using random effects models. Thirteen cohort studies were included. The summary relative risk was 1.21 (95% CI 1.12–1.30, I2 = 76%, n = 8) per 5 unit increment in BMI, 1.16 (95% CI 1.12–1.19, I2 = 0%, n = 5) per 10 cm increase in waist circumference, 1.06 (95% CI 1.04–1.08, I2 = 67%, n = 3) per 5 kg increase in weight and 1.12 (95% CI 1.06–1.18, I2 = 86%, n = 3) per 5 kg of weight gain. The summary RR was 1.16 (95% CI 1.03–1.31, I2 = 51%, n = 10) for participants with diabetes compared to participants without diabetes, and 0.93 (95% CI 0.78–1.10, I2 = 80%, n = 4) for high vs. low physical activity. These results suggest a positive association between adiposity and diabetes and the risk of kidney stones, but no association with physical activity. The online version of this article (10.1007/s10654-018-0426-4) contains supplementary material, which is available to authorized users.
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影响因子：
5
作者：
GREENLAND, S;LONGNECKER, MP
通讯作者：
LONGNECKER, MP
影响因子：
2.9
作者：
Hippisley-Cox, Julia;Coupland, Carol
通讯作者：
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影响因子：
15.9
作者：
DEFRONZO, RA;COOKE, CR;DAVIS, PJ
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DAVIS, PJ
影响因子：
4.9
作者：
Landgren AJ;Jacobsson LTH;Lindström U;Sandström TZS;Drivelegka P;Björkman L;Fjellstedt E;Dehlin M
通讯作者：
Dehlin M
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N