The association of health literacy with adherence and outcomes in moderate-severe asthma.

The association of health literacy with adherence and outcomes in moderate-severe asthma.
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DOI:
10.1016/j.jaci.2013.02.014
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发表时间:
2013-08
影响因子:
14.2
通讯作者:
Morales, Knashawn H.
Morales, Knashawn H.
中科院分区:
医学1区
文献类型:
--
作者:
Apter, Andrea J.;Wan, Fei;Reisine, Susan;Bender, Bruce;Rand, Cynthia;Bogen, Daniel K.;Bennett, Ian M.;Bryant-Stephens, Tyra;Roy, Jason;Gonzalez, Rodalyn;Priolo, Chantel;Ten Have, Thomas;Morales, Knashawn H.

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Low health literacy is associated with poor outcomes in asthma and other diseases but the mechanisms governing this relationship are not well-defined. To assess whether literacy is related to subsequent asthma self-management, measured as adherence to inhaled steroids, and asthma outcomes. In a prospective longitudinal cohort study, numeric (Asthma Numeracy Questionnaire (ANQ)) and print literacy (Short Test of Functional Health Literacy in Adults (S-TOFHLA)) were assessed at baseline in adults with moderate or severe asthma for their impact on subsequent electronically monitored adherence and asthma outcomes (asthma control, asthma-related quality of life, and FEV1) over 26 weeks, using mixed-effects linear regression models. 284 adults participated: 48±14 years, 71% female, 70% African American, 6% Latino, mean FEV1 66% ± 19%, 86 (30%) with hospitalizations and 148 (52%) with ED visits for asthma in the prior year. Mean ANQ score (range 0–4) was 2.3 ± 1.2; mean S-TOFHLA score 31 ± 8 (range 0–36). In unadjusted analyses numeric and print literacy were associated with better adherence (p=0.01, p=0.08), asthma control (p=0.005, p <0.001), and quality of life (p<0.001, p<0.001). After controlling for age, sex, and race/ethnicity, the associations diminished and only quality of life (numeric: p=0.03, print p=0.006) and asthma control (print p=0.005) remained significantly associated with literacy. Race/ethnicity, income, and educational attainment were correlated (p<0.001). While the relationship between literacy and health is complex, interventions which account for and address the literacy needs of patients may improve asthma outcomes. In adults with moderate or severe asthma, higher health literacy scores were associated with better subsequent quality of life and asthma control.
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