Assay of Growth Hormone Levels in Human Plasma using Commercial Kits: Analysis of Some Factors Influencing the Results

Assay of Growth Hormone Levels in Human Plasma using Commercial Kits: Analysis of Some Factors Influencing the Results
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使用商业试剂盒测定人血浆中的生长激素水平:影响结果的一些因素分析

DOI:
10.1111/j.1651-2227.1990.tb11673.x
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发表时间:
1990
期刊:
Acta Pædiatrica
影响因子:
--
通讯作者:
J.CI. Job
J.CI. Job
中科院分区:
--
文献类型:
--
作者:
P. Chatelain;B. Bouillat;R. Cohen;G. Sassolas;J. Souberbielle;A. Ruitton;M. Joly;J.CI. Job

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抽象的。对39个不同实验室使用5种不同的免疫试剂盒进行的生长激素(GH)检测的可靠性进行了评估。结果发现,不同商业试剂盒测定的生长激素水平的差异可能是由于人为因素以及试剂盒之间的差异。此外,还评估了在激发试验和自发分泌发作期间循环GH量的变化对GH测定结果的影响。一些试剂盒可能低估了大分子形式的生长激素。
ABSTRACT. The reliability of growth hormone (GH) assays, performed in 39 different laboratories, using five different immunoassay kits was evaluated. It was found that the variability in GH levels measured by different commercial assay kits may be due to human factors, as well as differences between the kits. The influence of the variation in amount of circulating GH, during provocative testing and spontaneous secretory episodes, on the results of GH assay was also evaluated. It was found that large molecular weight forms of GH may be underestimated by some assay kits.
体内分泌的人类生长激素的分子形式:分泌刺激的非特异性。
DOI: 10.1210/jcem-62-4-789
发表时间: 1986
期刊: The Journal of clinical endocrinology and metabolism
影响因子: --
作者:
Baumann,G;Stolar,MW
通讯作者: Stolar,MW
身材矮小诊断和治疗的进展,特别提到生长激素的作用。
DOI: 10.1016/s0022-3476(84)80472-2
发表时间: 1984
期刊: The Journal of pediatrics
影响因子: --
作者:
Schaff-Blass,E;Burstein,S;Rosenfield,RL
通讯作者: Rosenfield,RL