Role of Diaphragmatic, Visceral, and Parietal Pathways in Peritoneal Fluid Absorption in Rat Peritoneal Dialysis
Role of Diaphragmatic, Visceral, and Parietal Pathways in Peritoneal Fluid Absorption in Rat Peritoneal Dialysis
复制标题
膈肌、内脏和顶叶通路在大鼠腹膜透析腹膜液体吸收中的作用
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
T. Sakai
中科院分区：
文献类型：
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作者：
K. Kumano;Kimitoshi Go;Mellin He;T. Sakai
评估了淋巴液和非淋巴液吸收对腹腔液体净损失的贡献。使用大鼠模型检查横膈膜与肝脏的粘连、内脏和顶叶通路，并将这两种方法结合使用，不进行治疗。在每种情况下，使用6只大鼠，每只大鼠用克雷布斯-林格溶液透析180分钟。腹腔净液体吸收率（PNFAR）是根据1251-牛血清白蛋白（BSA）从腹腔消失而确定的，淋巴吸收率（LAR）是根据这种白蛋白在血液中的出现而确定的。78%的净液体流失是通过非淋巴途径发生的，主要是通过顶骨和内脏吸收，剩下的22%是通过淋巴，主要途径是膈下淋巴。因此，非淋巴液吸收似乎是大鼠腹膜透析中腹腔液体流失的主要途径。
Assessment was made of the contribution of lymphatic and non lymphatic fluid absorption to net fluid loss from the peritoneal cavity. Diaphragmatic, visceral, and parietal pathways in lymphatics and nonlymphatics were examined using a rat model with adhesion of the diaphragm to the liver, evisceration, these two procedures in combination, and without treatment. In each of these cases, six rats were used, each dialyzed for 180 min with Krebs–Ringer solution. The peritoneal net fluid absorption rate (PNFAR) was determined based on the disappearance of 1251-bovine serum albumin (BSA) from the peritoneal cavity and the lymphatic absorption rate (LAR), was based on the appearance of this albumin in the blood. Seventy-eight percent of net fluid loss occurred via the non lymphatic pathway, primarily through parietal and visceral absorption, and the remaining 22% through the lymphatics, the main pathway being the subdiaphragmatic lymphatics. Nonlymphatic fluid absorption would thus appear to be a major route of fluid loss from the peritoneal cavity in rat peritoneal dialysis.
小鼠腹膜吸收的淋巴和非淋巴途径：生理学与病理学。
影响因子：
3
作者：
Nagy,JA
通讯作者：
Nagy,JA