Age-Related Deficits in Electrophysiological and Behavioral Measures of Binaural Temporal Processing.
Age-Related Deficits in Electrophysiological and Behavioral Measures of Binaural Temporal Processing.
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DOI：
10.3389/fnins.2020.578566
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发表时间：
2020
影响因子：
4.3
通讯作者：
Billings CJ
中科院分区：
文献类型：
--
作者：
Koerner TK;Muralimanohar RK;Gallun FJ;Billings CJ
双耳处理，特别是双耳相位差的处理，对于背景噪声中的声音定位和语音理解是重要的。年龄已经被证明会影响这些双耳时间线索的神经编码和感知，即使在临床听力正常的个体中也是如此。这项工作使用了一种新的电生理反应，称为耳间相位调制跟随反应（IPM-FR），以检查年龄对耳间相位差线索的神经编码的影响。双耳处理的几个行为措施的神经记录和性能之间的关系被用来确定是否IPM-FR是预测耳间相位差敏感性和功能性语音理解缺陷。行为双耳频率调制检测阈值进行了测量，以评估耳间相位差的敏感性，而空间释放掩蔽阈值被用来评估空间化噪声的语音理解能力。30名年龄在35岁至74岁之间，低频听阈正常的成年人被用于这项研究。数据显示，与年轻参与者相比，老年参与者对耳间相位差线索的神经反应较弱，并且不太能够利用双耳线索来理解语音。结果还表明，IPM-FR是预测性能的双耳调频检测任务，但不是空间释放掩蔽任务后，会计年龄的影响。这些结果证实了以前的工作表明，IPM-FR反映了年龄相关的下降双耳时间处理，并提供了进一步的证据表明，这种反应可能是一个有用的客观工具，用于评估双耳功能。然而，还需要进一步的研究来了解IPM-FR与语音理解能力的关系。
Binaural processing, particularly the processing of interaural phase differences, is important for sound localization and speech understanding in background noise. Age has been shown to impact the neural encoding and perception of these binaural temporal cues even in individuals with clinically normal hearing sensitivity. This work used a new electrophysiological response, called the interaural phase modulation-following response (IPM-FR), to examine the effects of age on the neural encoding of interaural phase difference cues. Relationships between neural recordings and performance on several behavioral measures of binaural processing were used to determine whether the IPM-FR is predictive of interaural phase difference sensitivity and functional speech understanding deficits. Behavioral binaural frequency modulation detection thresholds were measured to assess sensitivity to interaural phase differences while spatial release-from-masking thresholds were used to assess speech understanding abilities in spatialized noise. Thirty adults between the ages of 35 to 74 years with normal low-frequency hearing thresholds were used in this study. Data showed that older participants had weaker neural responses to the interaural phase difference cue and were less able to take advantage of binaural cues for speech understanding compared to younger participants. Results also showed that the IPM-FR was predictive of performance on the binaural frequency modulation detection task, but not on the spatial release-from-masking task after accounting the effects of age. These results confirm previous work that showed that the IPM-FR reflects age-related declines in binaural temporal processing and provide further evidence that this response may represent a useful objective tool for assessing binaural function. However, further research is needed to understand how the IPM-FR is related to speech understanding abilities.
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DOI：
10.1121/1.2998779
发表时间：
2008-12
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
He NJ;Mills JH;Ahlstrom JB;Dubno JR
通讯作者：
Dubno JR
影响因子：
2.4
作者：
Bolia, RS;Nelson, WT;Simpson, BD
通讯作者：
Simpson, BD
影响因子：
16.6
作者：
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通讯作者：
Kraus, Nina
DOI：
10.1044/2019_jslhr-h-18-0217
发表时间：
2019-06-01
影响因子：
2.6
作者：
Hoover, Eric C.;Kinney, Brianna N.;Eddins, David A.
通讯作者：
Eddins, David A.
影响因子：
2.4
作者：
HARTMANN, WM;KLEIN, MA
通讯作者：
KLEIN, MA