New insights from Thailand into the maternal genetic history of Mainland Southeast Asia.

New insights from Thailand into the maternal genetic history of Mainland Southeast Asia.
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DOI:
10.1038/s41431-018-0113-7
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发表时间:
2018-06
期刊:
European journal of human genetics : EJHG
影响因子:
--
通讯作者:
Stoneking M
Stoneking M
中科院分区:
其他
文献类型:
--
作者:
Kutanan W;Kampuansai J;Brunelli A;Ghirotto S;Pittayaporn P;Ruangchai S;Schröder R;Macholdt E;Srikummool M;Kangwanpong D;Hübner A;Arias L;Stoneking M

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Tai-Kadai(TK)是东南亚大陆(MSEA)的主要语系之一,主要集中在泰国和老挝地区。我们先前对1234个mtDNA基因组序列的研究支持了TK语言从中国南部向老挝以及泰国北方和东北部传播的流行扩散情景。在这里,我们添加了来自22个群体的560个mtDNA基因组,重点是讲TK的泰国中部人民和讲汉藏语的克伦人。我们发现了广泛的多样性,包括62个单倍型群以前没有报告从这个地区。Demic扩散仍然是泰国中部的一个更好的方案,强调传统知识的人通过MSEA的扩展,虽然也有一些支持基因流动之间的泰国中部和本地的Austroasiatic讲孟和高棉。我们还测试了竞争模型的遗传关系的群体从主要的MSEA语言,并发现支持的祖先关系的传统知识和讲南岛语的群体。
Tai-Kadai (TK) is one of the major language families in Mainland Southeast Asia (MSEA), with a concentration in the area of Thailand and Laos. Our previous study of 1234 mtDNA genome sequences supported a demic diffusion scenario in the spread of TK languages from southern China to Laos as well as northern and northeastern Thailand. Here we add an additional 560 mtDNA genomes from 22 groups, with a focus on the TK-speaking central Thai people and the Sino-Tibetan speaking Karen. We find extensive diversity, including 62 haplogroups not reported previously from this region. Demic diffusion is still a preferable scenario for central Thais, emphasizing the expansion of TK people through MSEA, although there is also some support for gene flow between central Thai and native Austroasiatic speaking Mon and Khmer. We also tested competing models concerning the genetic relationships of groups from the major MSEA languages, and found support for an ancestral relationship of TK and Austronesian-speaking groups.
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