Farnesoid X Receptor Constructs an Immunosuppressive Microenvironment and Sensitizes FXRhighPD-L1low NSCLC to Anti–PD-1 Immunotherapy
Farnesoid X Receptor Constructs an Immunosuppressive Microenvironment and Sensitizes FXRhighPD-L1low NSCLC to Anti–PD-1 Immunotherapy
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Farnesoid X 受体构建免疫抑制微环境并使 FXRhighPD-L1low NSCLC 对抗 PD-1 免疫疗法敏感
DOI:
10.1158/2326-6066.cir-17-0672
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发表时间:
2019-04
影响因子:
10.1
通讯作者:
ong Jiang
中科院分区:
文献类型:
--
作者:
Wenjie You;Lijun Li;Deqiao Sun;Xueqing Liu;Zongjun Xia;Shan Xue;Bi Chen;Hui Qin;Jing Ai;H;ong Jiang
A subtype of non-small cell lung cancer is characterized by immunosuppression through the farnesoid X receptor (FXR) and responsiveness to anti–PD-1 therapy. The combination of high FXR expression and low PD-L1 expression may identify patients receptive t
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DOI:
10.1891/9780826121646.0002
发表时间:
2018-09
期刊:
Cancer Rehabilitation
影响因子:
--
作者:
K. Miller;R. Siegel;R. Khan;A. Jemal
通讯作者:
K. Miller;R. Siegel;R. Khan;A. Jemal
影响因子:
11.5
作者:
Konishi, J;Yamazaki, K;Nishimura, M
通讯作者:
Nishimura, M
影响因子:
120.7
作者:
Kris, Mark G.;Johnson, Bruce E.;Berry, Lynne D.;Kwiatkowski, David J.;Iafrate, A. John;Wistuba, Ignacio I.;Varella-Garcia, Marileila;Franklin, Wilbur A.;Aronson, Samuel L.;Su, Pei-Fang;Shyr, Yu;Camidge, D. Ross;Sequist, Lecia V.;Glisson, Bonnie S.;Khuri, Fadlo R.;Garon, Edward B.;Pao, William;Rudin, Charles;Schiller, Joan;Haura, Eric B.;Socinski, Mark;Shirai, Keisuke;Chen, Heidi;Giaccone, Giuseppe;Ladanyi, Marc;Kugler, Kelly;Minna, John D.;Bunn, Paul A.
通讯作者:
Bunn, Paul A.
影响因子:
7.3
作者:
Wimmers F;Schreibelt G;Sköld AE;Figdor CG;De Vries IJ
通讯作者:
De Vries IJ
影响因子:
4.8
作者:
Laffitte, BA;Kast, HR;Edwards, PA
通讯作者:
Edwards, PA