Differential effects of three enteral dietary regimens on selected outcome variables in burn patients.
Differential effects of three enteral dietary regimens on selected outcome variables in burn patients.
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三种肠内饮食方案对烧伤患者选定结果变量的不同影响。
DOI：
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
J. Alexander
中科院分区：
文献类型：
--
作者：
M. Gottschlich;M. Jenkins;G. Warden;Theresa Baumer;Pamela Havens;J. Snook;J. Alexander
模块化管喂养配方（MTF）的设计，以满足烧伤患者独特的营养需求，应用原则以前记录在我们的烧伤豚鼠模型。MTF是一种高蛋白、低脂、限制亚油酸的配方，富含omega-3脂肪酸、精氨酸、半胱氨酸、组氨酸、维生素a、锌和抗坏血酸。50例3 ~ 76岁烧伤患者，体表面积10% ~ 89%，前瞻性随机分为三组，随机比较MTF和两种广泛应用于烧伤营养支持的肠内方案。年龄、总烧伤和三度烧伤百分比、静息能量消耗、卡路里和蛋白质摄入量在所有组中相似。数据分析显示，MTF在减少伤口感染（p < 0.03）和住院时间/烧伤百分比（p < 0.02）方面具有显著优势。MTF还与降低腹泻发生率、改善葡萄糖耐量、降低血清甘油三酯、减少感染发作总数和改善肌肉质量保存的趋势相关，尽管没有达到统计学意义。70%的死亡发生在摄入大剂量脂肪和亚油酸的那一组。结合这些观察结果，我们相信MTF在调节对烧伤的改善反应方面是有效的。
A modular tube feeding recipe (MTF) was designed to meet the unique nutritional needs of burn patients, applying principles previously documented in our burned guinea pig model. MTF, a high-protein, low-fat, linoleic acid-restricted formulation is enriched with omega-3 fatty acids, arginine, cysteine, histidine, vitamin A, zinc, and ascorbic acid. Fifty patients, 3 to 76 years of age with burns ranging from 10 to 89% total body surface area were prospectively randomized into three groups which blindly compared MTF to two enteral regimens widely utilized in the nutritional support of burns. Age, percent total and third-degree burn, resting energy expenditure, and calorie and protein intake were similar in all groups. Data analysis demonstrated significant superiority of MTF in the reduction of wound infection (p less than 0.03) and length of stay/percent burn (p less than 0.02). MTF was also associated with a decreased incidence of diarrhea, improved glucose tolerance, lower serum triglycerides, reduced total number of infectious episodes and trends toward improved preservation of muscle mass, although statistical significance was not achieved. Seventy percent of deaths occurred in the group supported with an inherently large dose of fat and linoleic acid. Combining these observations, it is believed that MTF is effective in modulating an improved response to burn injury.
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影响因子：
39.2
作者：
GLAUBER, H;WALLACE, P;BRECHTEL, G
通讯作者：
BRECHTEL, G
鱼油对烧伤后代谢和免疫力的影响。
DOI：
10.1177/0148607187011006521
发表时间：
1987
期刊：
JPEN. Journal of parenteral and enteral nutrition
影响因子：
--
作者：
Trocki,O;Heyd,TJ;Waymack,JP;Alexander,JW
通讯作者：
Alexander,JW
完整蛋白质与游离氨基酸在热损伤动物营养支持中的比较。
DOI：
10.1177/0148607186010002139
发表时间：
1986
期刊：
JPEN. Journal of parenteral and enteral nutrition
影响因子：
--
作者：
Trocki,O;Mochizuki,H;Dominioni,L;Alexander,JW
通讯作者：
Alexander,JW
热损伤后肠内饮食的最佳脂质含量。
DOI：
10.1177/0148607184008006638
发表时间：
1984
期刊：
JPEN. Journal of parenteral and enteral nutrition
影响因子：
--
作者：
Mochizuki,H;Trocki,O;Dominioni,L;Ray,MB;Alexander,JW
通讯作者：
Alexander,JW
通过早期肠内喂养减少烧伤后代谢亢进。
DOI：
--
发表时间：
1985
期刊：
Current surgery
影响因子：
--
作者：
Mochizuki,H;Trocki,O;Dominioni,L;Alexander,JW
通讯作者：
Alexander,JW