Redox-active antibiotics enhance phosphorus bioavailability.
Redox-active antibiotics enhance phosphorus bioavailability.
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DOI:
10.1126/science.abd1515
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发表时间:
2021-03-05
期刊:
影响因子:
--
通讯作者:
Newman DK
中科院分区:
文献类型:
--
作者:
McRose DL;Newman DK
Microbial production of antibiotics is common but our understanding of their roles in the environment is limited. Here, we explore long-standing observations that microbes increase production of redox-active antibiotics under phosphorus limitation. The availability of phosphorus, a nutrient required by all life on Earth and essential for agriculture, can be controlled by adsorption to and release from iron minerals via redox cycling. Using phenazine antibiotic production by pseudomonads as a case study, we show that phenazines are regulated by phosphorus and solubilize phosphate via reductive dissolution of iron oxides in the lab and field, concomitantly increasing microbial growth. Phenazines are just one of many examples of phosphorus-regulated antibiotics. Our work suggests a widespread but previously unappreciated role for redox-active antibiotics in phosphorus acquisition and cycling. Antibiotics enhance P bioavailability.
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DOI:
10.1016/j.cub.2020.08.005
发表时间:
2020-10-05
期刊:
Current biology : CB
影响因子:
--
作者:
Dahlstrom KM;McRose DL;Newman DK
通讯作者:
Newman DK
影响因子:
48
作者:
Gibson, Daniel G.;Young, Lei;Smith, Hamilton O.
通讯作者:
Smith, Hamilton O.
影响因子:
10.5
作者:
Glasser NR;Saunders SH;Newman DK
通讯作者:
Newman DK
影响因子:
2.8
作者:
CROSBY, SA;MILLWARD, GE;WHITFIELD, M
通讯作者:
WHITFIELD, M
DOI:
10.1128/aem.19.1.109-112.1970
发表时间:
1970-01-01
期刊:
APPLIED MICROBIOLOGY
影响因子:
--
作者:
HALL, MJ;HASSALL, CH
通讯作者:
HASSALL, CH