Keystone metabolites of crop rhizosphere microbiomes.
Keystone metabolites of crop rhizosphere microbiomes.
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DOI：
10.1016/j.cub.2020.08.005
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发表时间：
2020-10-05
期刊：
影响因子：
--
通讯作者：
Newman DK
中科院分区：
文献类型：
--
作者：
Dahlstrom KM;McRose DL;Newman DK
微生物在维持农业植物生长中的作用对人类繁荣具有巨大的潜在影响。然而，我们对根际微生物群落的基本功能以及它们在未来压力下可能如何变化的了解并不完全，更不用说如何利用这些过程来维持或提高作物产量了。还原论的方法可能有助于产生和测试的假设，最终可以转化为农业实践。考虑到这一点，我们问一些根际微生物群落是否可能由“关键代谢物”，设想在这里作为微生物产生的分子，通过抗生素和/或生长促进性能，可能会发挥巨大的作用，在塑造社会的发展时空。为了说明这一点，我们使用氧化还原活性代谢物的例子，特别是吩嗪，它是由农业土壤中发现的许多细菌产生的，具有众所周知的催化特性。吩嗪可以作为针对各种细胞类型的有效抗生素，但它们也可以促进必需无机营养素的获得。在这篇文章中，我们提出了这些代谢物可能影响微生物群落和最终农业生产力的两种具体情况：i）在日益干旱的作物土壤中对有益和致病真菌的生物控制和ii）促进磷的生物利用度和可持续的肥料使用。最后，我们对未来的研究提出了具体的建议。
The role of microbes in sustaining agricultural plant growth has great potential consequences for human prosperity. Yet we have an incomplete understanding of the basic function of rhizosphere microbial communities and how they may change under future stresses, let alone how these processes might be harnessed to sustain or improve crop yields. A reductionist approach may aid the generation and testing of hypotheses that can ultimately be translated to agricultural practices. With this in mind, we ask whether some rhizosphere microbial communities might be governed by “keystone metabolites”, envisioned here as microbially produced molecules that, through antibiotic and/or growth-promoting properties, may play an outsized role in shaping the development of the community spatiotemporally. To illustrate this point, we use the example of redox-active metabolites, and in particular phenazines, which are produced by many bacteria found in agricultural soils and have well-understood catalytic properties. Phenazines can act as potent antibiotics against a variety of cell types, yet they also can promote the acquisition of essential inorganic nutrients. In this essay, we suggest the ways these metabolites might affect microbial communities and ultimately agricultural productivity in two specific scenarios: i) biocontrol of beneficial and pathogenic fungi in increasingly arid crop soils and ii) promotion of phosphorus bioavailability and sustainable fertilizer use. We conclude with specific proposals for future research.
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DOI：
10.1073/pnas.1719588115
发表时间：
2018-03-06
影响因子：
11.1
作者：
Morris JL;Puttick MN;Clark JW;Edwards D;Kenrick P;Pressel S;Wellman CH;Yang Z;Schneider H;Donoghue PCJ
通讯作者：
Donoghue PCJ
影响因子：
5.2
作者：
Simionato AS;Navarro MOP;de Jesus MLA;Barazetti AR;da Silva CS;Simões GC;Balbi-Peña MI;de Mello JCP;Panagio LA;de Almeida RSC;Andrade G;de Oliveira AG
通讯作者：
de Oliveira AG
影响因子：
4.4
作者：
Mavrodi, Dmitri V.;Mavrodi, Olga V.;Weller, David M.
通讯作者：
Weller, David M.
影响因子：
6.7
作者：
Lobell, David B.;Field, Christopher B.
通讯作者：
Field, Christopher B.
影响因子：
3.6
作者：
Mucha J;Peay KG;Smith DP;Reich PB;Stefański A;Hobbie SE
通讯作者：
Hobbie SE