Crosstalk Between Autophagy and Ferroptosis and Its Putative Role in Ischemic Stroke.
Crosstalk Between Autophagy and Ferroptosis and Its Putative Role in Ischemic Stroke.
复制标题
自噬和铁死亡之间的串扰及其在缺血性中风中的假定作用
DOI：
10.3389/fncel.2020.577403
复制
发表时间：
2020
影响因子：
5.3
通讯作者：
Yang Y
中科院分区：
文献类型：
--
作者：
Liu J;Guo ZN;Yan XL;Huang S;Ren JX;Luo Y;Yang Y
Autophagy is a conserved process to maintains homeostasis via the degradation of toxic cell contents, which can either promote cell survival or accelerate cellular demise. Ferroptosis is a recently discovered iron-dependent cell death pathway associated with the accumulation of lethal reactive lipid species. In the past few years, an increasing number of studies have suggested the crosstalk between autophagy and ferroptosis. Ischemic stroke is a complex brain disease regulated by several cell death pathways, including autophagy and ferroptosis. However, the potential links between autophagy and ferroptosis in ischemic stroke have not yet been explored. In this review, we briefly overview the mechanisms of ferroptosis and autophagy, as well as their possible connections in ischemic stroke. The elucidation of crosstalk between different cell death pathways may provide insight into new future ischemic stroke therapies.
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影响因子：
8.3
作者：
Baek SH;Noh AR;Kim KA;Akram M;Shin YJ;Kim ES;Yu SW;Majid A;Bae ON
通讯作者：
Bae ON
影响因子：
64.5
作者：
Dixon SJ;Lemberg KM;Lamprecht MR;Skouta R;Zaitsev EM;Gleason CE;Patel DN;Bauer AJ;Cantley AM;Yang WS;Morrison B 3rd;Stockwell BR
通讯作者：
Stockwell BR
DOI：
10.3390/molecules20058742
发表时间：
2015-05-14
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Aoyama K;Nakaki T
通讯作者：
Nakaki T
影响因子：
5.1
作者：
Beker, Mustafa Caglar;Caglayan, Berrak;Kilic, Ertugrul
通讯作者：
Kilic, Ertugrul
影响因子：
4.2
作者：
Cheng, Jing;Fan, Yan-Qin;Chen, Qian-Xue
通讯作者：
Chen, Qian-Xue