A Reactivity-Driven Approach to the Discovery and Development of Gold-Catalyzed Organic Reactions.

A Reactivity-Driven Approach to the Discovery and Development of Gold-Catalyzed Organic Reactions.
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DOI:
10.1055/s-0029-1219369
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发表时间:
2010-03-01
期刊:
Synlett : accounts and rapid communications in synthetic organic chemistry
影响因子:
--
通讯作者:
Toste FD
Toste FD
中科院分区:
其他
文献类型:
--
作者:
Shapiro ND;Toste FD

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有机化学的研究方法与它们描述的反应一样多。在本文中,我们描述了基于反应性的方法。以我们在金催化领域的工作为背景,我们讨论了对反应机制和反应范式的关注如何导致新合成工具的快速发现。
Approaches to research in organic chemistry are as numerous as the reactions they describe. In this account, we describe our reactivity-based approach. Using our work in the area of gold-catalysis as a background, we discuss how a focus on reaction mechanism and reactivity paradigms can lead to the rapid discovery of new synthetic tools.
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