On-line matrix addition for detecting aerosol particles

On-line matrix addition for detecting aerosol particles
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用于检测气溶胶颗粒的在线基质添加

DOI:
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发表时间:
2006
期刊:
影响因子:
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通讯作者:
Weijun Zhang
Weijun Zhang
中科院分区:
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文献类型:
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作者:
Liu;Yuan Zhu;Xiao;Wenwu Zhao;Haiyang Zheng;X. Gu;L. Fang;Weijun Zhang

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通过基质辅助激光解吸/电离 (MALDI) 和气溶胶飞行时间质谱仪 (ATOFMS) 测量单个气溶胶颗粒。 ATOFMS 的入口与蒸发/冷凝流通池相连,允许通过冷凝到颗粒上来添加基质。涂层颗粒通过三级差动泵浦毛细管入口进入离子源,然后被聚焦的 266 nm Nd:YAG 激光电离。可以同时获得单个颗粒的质谱和空气动力学尺寸。在线基质添加技术使得实时识别生物气溶胶成为可能。
Single aerosol particles were measured by matrix-assisted laser desorption/ionization (MALDI) with an aerosol time-of-flight mass spectrometer (ATOFMS). The inlet to the ATOFMS was coupled with an evaporation/condensation flow cell that allowed matrix addition by condensation onto the particles. The coated particles entered the ion source through three-stage differentially pumped capillary inlet and were then ionized by a focused 266 nm Nd:YAG laser. The mass spectra and aerodynamic size of the single particles can be obtained simultaneously. The on-line matrix addition technique makes it possible to identify biological aerosols in real-time.
通过冷凝进行基质添加,用于收集的气溶胶颗粒的基质辅助激光解吸/电离。
DOI: 10.1021/ac020181i
发表时间: 2002
影响因子: 7.4
作者:
Jackson,ShelleyN;Murray,KermitK
通讯作者: Murray,KermitK