Epidemiology of Kaposi's Sarcoma.
Epidemiology of Kaposi's Sarcoma.
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DOI：
10.3390/cancers13225692
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发表时间：
2021-11-14
期刊：
影响因子：
5.2
通讯作者：
Costagliola D
中科院分区：
文献类型：
--
作者：
Grabar S;Costagliola D
Kaposi’s sarcoma is a rare tumor caused by human herpesvirus 8 in the context of immunodeficiency, such as that induced by HIV infection or immunosuppressive therapy. In patients living with HIV (PLHIV), thanks to potent antiretroviral treatment that efficiently restores immunity and allows a better control of HIV infection, the occurrence of KS has decreased dramatically over the past 25 years. However, KS is still one the most frequent cancers in PLHIV, in particular in men who have sex with men and in sub-Saharan Africa, where it is still endemic. Even in the context of restored immunity, the risk of KS is still more than 30 times higher in PLHIV than in the general population. Kaposi’s sarcoma is an angioproliferative tumor caused by human herpesvirus 8 in the context of immunodeficiency, such as that induced by HIV infection or immunosuppressive therapy. Its incidence has dramatically fallen in patients living with HIV (PLHIV) since the introduction of potent antiretroviral combinations 25 years ago due to the restoration of immunity and better control of HIV replication. However, KS is still one of the most frequently occurring cancers in PLHIV, in particular in men who have sex with men and in sub-Saharan Africa, where it is still endemic. Even in the context of restored immunity, the risk of KS is still more than 30 times higher in PLHIV than in the general population. Recent evidence indicates that early initiation of antiretroviral treatment, which is recommended by current guidelines, may reduce the risk of KS but it needs to be accompanied by early access to care. This review mainly focuses on the recent epidemiological features of KS in the context of HIV infection.
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影响因子：
6.4
作者：
Blumenthal, Melissa J.;Schutz, Charlotte;Schafer, Georgia
通讯作者：
Schafer, Georgia
影响因子：
11.1
作者：
Blumenthal MJ;Cornejo Castro EM;Whitby D;Katz AA;Schäfer G
通讯作者：
Schäfer G
DOI：
10.1097/qai.0000000000001394
发表时间：
2017-08-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Dubrow R;Qin L;Lin H;Hernández-Ramírez RU;Neugebauer RS;Leyden W;Althoff KN;Achenbach CJ;Hessol NA;Modur SP;DʼSouza G;Bosch RJ;Grover S;Horberg MA;Kitahata MM;Mayor AM;Novak RM;Rabkin CS;Sterling TR;Goedert JJ;Justice AC;Engels EA;Moore RD;Silverberg MJ;North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS
通讯作者：
North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS
影响因子：
39.2
作者：
Chammartin, Frederique;Lodi, Sara;Bucher, Heiner C.
通讯作者：
Bucher, Heiner C.
影响因子：
120.7
作者：
Engels, Eric A.;Pfeiffer, Ruth M.;Fraumeni, Joseph F., Jr.;Kasiske, Bertram L.;Israni, Ajay K.;Snyder, Jon J.;Wolfe, Robert A.;Goodrich, Nathan P.;Bayakly, A. Rana;Clarke, Christina A.;Copeland, Glenn;Finch, Jack L.;Fleissner, Mary Lou;Goodman, Marc T.;Kahn, Amy;Koch, Lori;Lynch, Charles F.;Madeleine, Margaret M.;Pawlish, Karen;Rao, Chandrika;Williams, Melanie A.;Castenson, David;Curry, Michael;Parsons, Ruth;Fant, Gregory;Lin, Monica
通讯作者：
Lin, Monica