Use and limitations of malaria rapid diagnostic testing by community health workers in war-torn Democratic Republic of Congo.
Use and limitations of malaria rapid diagnostic testing by community health workers in war-torn Democratic Republic of Congo.
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DOI：
10.1186/1475-2875-8-308
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发表时间：
2009-12-23
期刊：
影响因子：
3
通讯作者：
Masumbuko CK
中科院分区：
文献类型：
--
作者：
Hawkes M;Katsuva JP;Masumbuko CK
准确和实用的疟疾诊断，如免疫层析快速诊断测试，有可能避免不必要的治疗和拯救生命。志愿社区卫生工作者是一种潜在的宝贵人力资源，可以将这项技术推广到最需要的地方，即撒哈拉以南非洲卫生设施和人员有限的偏远农村社区。本研究报告的培训计划，为CHW纳入RDTs到他们的管理战略，发热儿童在刚果，一个热带非洲环境的人类冲突蹂躏的民主共和国。前瞻性队列研究、满意度问卷调查和决策分析。12名CHW接受了安全准确地执行和解释RDT的培训，然后在357名发热儿童的队列中成功地在其偏远社区实施了快速诊断测试。CHW在评价RDT的实用性和易用性方面一致为阳性。然而，在这一队列中的高疟疾患病率（RDTs为93%，光学显微镜为88%）限制了RDTs的成本效益相比，所有发热儿童的假定治疗，从一个简化的决策分析的结果证明。社区卫生工作者可以安全有效地使用RDT管理发热儿童;然而，RDT的成本效益在疟疾高发区是有限的。
Accurate and practical malaria diagnostics, such as immunochromatographic rapid diagnostic tests (RDTs), have the potential to avert unnecessary treatments and save lives. Volunteer community health workers (CHWs) represent a potentially valuable human resource for expanding this technology to where it is most needed, remote rural communities in sub-Saharan Africa with limited health facilities and personnel. This study reports on a training programme for CHWs to incorporate RDTs into their management strategy for febrile children in the Democratic Republic of Congo, a tropical African setting ravaged by human conflict. Prospective cohort study, satisfaction questionnaire and decision analysis. Twelve CHWs were trained to safely and accurately perform and interpret RDTs, then successfully implemented rapid diagnostic testing in their remote community in a cohort of 357 febrile children. CHWs were uniformly positive in evaluating RDTs for their utility and ease of use. However, high malaria prevalence in this cohort (93% by RDTs, 88% by light microscopy) limited the cost-effectiveness of RDTs compared to presumptive treatment of all febrile children, as evidenced by findings from a simplified decision analysis. CHWs can safely and effectively use RDTs in their management of febrile children; however, cost-effectiveness of RDTs is limited in zones of high malaria prevalence.
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影响因子：
3
作者：
Zikusooka, Charlotte M.;McIntyre, Diane;Barnes, Karen I.
通讯作者：
Barnes, Karen I.
影响因子：
64.8
作者：
Rafael, Maria E;Taylor, Terrie;Allan, Richard
通讯作者：
Allan, Richard
DOI：
10.2471/blt.07.042259
发表时间：
2008-02-01
期刊：
Bulletin of the World Health Organization: International Journal of Public Health
影响因子：
--
作者：
Shillcutt, Samuel;Morel, Chantal;Mills, A
通讯作者：
Mills, A
影响因子：
5.2
作者：
Hashizume, M;Kondo, H;Wakai, S
通讯作者：
Wakai, S
DOI：
10.4269/ajtmh.2001.65.883
发表时间：
2001-12-01
影响因子：
3.3
作者：
Pang, LW;Piovesan-Alves, F
通讯作者：
Piovesan-Alves, F