Elucidating the underlying components of food valuation in the human orbitofrontal cortex.
Elucidating the underlying components of food valuation in the human orbitofrontal cortex.
复制标题
DOI:
10.1038/s41593-017-0008-x
复制
发表时间:
2017-12
影响因子:
25
通讯作者:
O'Doherty JP
中科院分区:
文献类型:
--
作者:
Suzuki S;Cross L;O'Doherty JP
The valuation of food is a fundamental component of our decision-making. Yet, little is known about how value signals for food and other rewards are constructed by the brain. Utilizing a food-based decision task in human participants, we found that subjective values can be predicted from beliefs about constituent nutritive attributes of food: protein, fat, carbohydrate and vitamin content. Multivariate analyses on fMRI data demonstrated that while food value is represented in patterns of neural activity in both medial and lateral parts of the orbitofrontal cortex (OFC), only the lateral OFC represents the elemental nutritive attributes. Effective connectivity analyses further indicate that information about the nutritive attributes represented in the lateral OFC is integrated within the medial OFC to compute an overall value. These findings provide a mechanistic account for the construction of food-value from its constituent nutrients.
登录
查看更多内容
DOI:
10.1002/bs.3830090304
发表时间:
1964-01-01
期刊:
BEHAVIORAL SCIENCE
影响因子:
--
作者:
BECKER, GM;DEGROOT, MH;MARSCHAK, J
通讯作者:
MARSCHAK, J
影响因子:
25
作者:
Kable, Joseph W.;Glimcher, Paul W.
通讯作者:
Glimcher, Paul W.
影响因子:
5.3
作者:
Gross, Jorg;Woelbert, Eva;Goebel, Rainer
通讯作者:
Goebel, Rainer
影响因子:
25
作者:
Chikazoe, Junichi;Lee, Daniel H.;Kriegeskorte, Nikolaus;Anderson, Adam K.
通讯作者:
Anderson, Adam K.
影响因子:
5.3
作者:
Hare, Todd A.;Malmaud, Jonathan;Rangel, Antonio
通讯作者:
Rangel, Antonio