Efficacy of Liquid Embolic Agent Treatment in Hemorrhagic Peripheral Intracranial Aneurysms: A Single-Center Experience.
Efficacy of Liquid Embolic Agent Treatment in Hemorrhagic Peripheral Intracranial Aneurysms: A Single-Center Experience.
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DOI：
10.3390/brainsci12091264
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发表时间：
2022-09-19
期刊：
影响因子：
3.3
通讯作者：
Zhang, Qing-Rong
中科院分区：
文献类型：
--
作者：
Zhuang, Zong;Zhu, Qi;Liu, Xun-Zhi;Ling, Hai-Ping;Na, Shi-Jie;Liu, Tao;Zhang, Yu-Hua;Hang, Chun-Hua;Liu, Kai-Dong;Zhang, Qing-Rong
关键词：
目的：评价液体栓塞剂治疗各种出血性颅内周围动脉瘤的疗效。研究方法：我们回顾性分析了38例患有出血性周围颅内动脉瘤并接受液体栓塞剂治疗的患者。术后6个月采用改良兰金量表进行随访，术后6个月进行数字减影血管造影随访。结果如下：38例（单纯外周动脉瘤10例，烟雾病（Moyamoya disease，MMD）6例，动静脉畸形（AVM）22例）中，后循环动脉瘤最多（57.9%），其次为前循环动脉瘤（21.1%）和颅内动脉瘤（21.1%）。4例发生术中出血，4例发生术后脑梗死，2例发生微导管留置，1例动静脉畸形患者基底动脉发生术中血栓形成。仅1例患者发生术后出血。在6个月随访时，84.2%的患者预后良好，13.5%的患者预后不良。结论：液体栓塞剂是治疗出血性颅内外周动脉瘤的有效药物，但其安全性取决于动脉瘤的亚型。对于MMD的外周出血性动脉瘤，栓塞前必须仔细评估血管结构。
Objective: To evaluate the efficacy of liquid embolization agents for treating various hemorrhagic peripheral intracranial aneurysms. Methods: We retrospectively analyzed 38 patients who suffered from hemorrhagic peripheral intracranial aneurysms and were treated with liquid embolization agents. We used the modified Rankin scale for follow-up at 6 months postoperatively, and digital subtraction angiography follow-up was performed 6 months postoperatively. Results: Of the 38 patients (ten of simple peripheral intracranial aneurysms, six of Moyamoya disease (MMD), and 22 of arteriovenous malformation (AVM)), posterior circulation accounted for the most significant proportion (57.9%), followed by anterior circulation (21.1%) and intranidal aneurysms (21.1%). Intraoperative hemorrhage occurred in four cases, postoperative cerebral infarction occurred in four cases, two patients encountered microcatheter retention, and intraoperative thrombosis took place in the basilar artery of a patient with an arteriovenous malformation. A postoperative hemorrhage occurred in only one patient. At 6-month follow-up, 84.2% of patients had good prognosis outcomes, and 13.5% had poor outcomes. Conclusion: Liquid embolization agents are effective for hemorrhagic peripheral intracranial aneurysms; however, safety depends on the subtypes. For peripheral hemorrhagic aneurysms in MMD, the vessel architecture must be carefully evaluated before embolization.
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影响因子：
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