Erectile dysfunction following treatments of benign prostatic hyperplasia: A prospective study
Erectile dysfunction following treatments of benign prostatic hyperplasia: A prospective study
复制标题
良性前列腺增生治疗后的勃起功能障碍：一项前瞻性研究
作者：
Uygur Mc;E. Gür;Arik Ai;U. Altuǧ;Demokan Erol
总结。本文对305例良性前列腺增生患者行开放性前列腺切除术、经尿道切除术、经尿道汽化、多沙唑嗪和非那雄胺对男性性功能的影响进行了研究。分别在治疗前、治疗后3、6个月用问卷对患者的性功能进行评估。共有212例（70%）患者在治疗前被判定为有效。3个月时，40例有效患者中2例（5%）和89例有效患者中5例（6%）分别出现开放性前列腺切除术和经尿道切除术导致勃起功能障碍。6个月时，前一组的1名患者和后一组的2名患者在3个月时出现了勃起功能障碍。在3个月的随访中，经尿道汽化导致14名有效患者中的4名（29%）勃起功能丧失，其中1名患者在6个月时恢复了勃起功能。33例使用doxazosin的患者中只有1例（3%）在3个月和6个月时失去勃起功能。在3个月的随访中，非那雄胺导致36例强效患者中8例（22%）勃起功能丧失。其中4例患者在使用非那雄胺3个月后接受了手术（经尿道切除术）。在6个月的随访中，又有4例患者出现勃起功能丧失。我们认为，在本研究调查的治疗方案中，非那雄胺和经尿道汽化具有最大的损害性功能的潜力，必须谨慎提供给强有力的患者
Summary. The effects of open prostatectomy, transurethral resection, transurethral vaporization, doxazosin and finasteride on sexual functions of men were investigated in a total of 305 patients with benign prostatic hyperplasia. The sexual functions of the patients were assessed with a questionnaire before treatment and 3 and 6 months after the treatment. A total of 212 (70%) patients were judged to be potent before the treatment. At 3 months, open prostatectomy and transurethral resection caused erectile dysfunction in 2 of 40 (5%) and 5 of 89 (6%) potent patients, respectively. At 6 months, one of the patients from the former and 2 of the patients from the latter groups who developed erectile dysfunction at 3 months stated improvement. Transurethral vaporization caused loss of erectile functions in 4 of 14 potent patients (29%) at the 3‐month follow‐up and, one of these patients recovered erectile functions at 6 months. Only one of the 33 patients (3%) using doxazosin stated that he lost his erectile functions both at 3 months and 6 months. At 3 months follow‐up, finasteride caused loss of erectile functions in 8 of 36 potent patients (22%). Four of these patients underwent surgery (transurethral resection) after 3 months of finasteride use. At the 6‐month follow‐up, 4 more patients suffered from loss of erectile functions. We suggest that finasteride and transurethral vaporization have the greatest potential of impairing the sexual functions among the treatment options investigated in this study and that they must be carefully offered to the potent patients.—
影响因子：
15.9
作者：
THIGPEN, AE;SILVER, RI;RUSSELL, DW
通讯作者：
RUSSELL, DW
影响因子：
6.6
作者：
BERRY, SJ;COFFEY, DS;EWING, LL
通讯作者：
EWING, LL