Functional analyses of mitoribosome 54S subunit devoid of mitochondria-specific protein sequences.
Functional analyses of mitoribosome 54S subunit devoid of mitochondria-specific protein sequences.
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DOI:
10.1002/yea.3678
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发表时间:
2022-03
期刊:
影响因子:
--
通讯作者:
Barros MH
中科院分区:
文献类型:
--
作者:
Santos B;Zeng R;Jorge SF;Ferreira-Junior JR;Barrientos A;Barros MH
A) Structure of the 54S subunit of the mitoribosome. Mitochondria-specific proteins are colored in yellow and those with bacterial homologs are in blue. The 21S rRNA is in gray. B) The mitochondria-specific extensions present in the conserved proteins are now colored in red. The extensions of uL3(N), uL4(C), uL5(C), uL13(C), bL17(C), bL19 (C), bL21(N), uL22(N), uL22(C) bL27(C), and uL30(N) showed in the panel represent some of the mitochondria-specific extensions studied in this work. →Study of the functional relevance of mit-specific extensions of mLSU proteins →Seven mit-specific extensions are not necessary for yeast respiratory growth. →Removal of extensions from 14 mtLSU resulted in unfunctional variants.
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