Electron microscopic localization of type I protein kinase C in rat Purkinje cells
Electron microscopic localization of type I protein kinase C in rat Purkinje cells
复制标题
大鼠浦肯野细胞中 I 型蛋白激酶 C 的电镜定位
DOI:
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发表时间:
1988
影响因子:
5.3
通讯作者:
Chikako Tanaka
中科院分区:
文献类型:
--
作者:
A. Kose;Naoaki Saito;H. Ito;U. Kikkawa;Yasutomi Nishizuka;Chikako Tanaka
A monoclonal antibody against protein kinase C (PKC) was used for immunocytochemical studies of the type I PKC encoded by gamma-cDNA sequence (gamma-subspecies) in rat Purkinje cells. Dense gamma- subspecies-like immunoreactivity was found on the cell membrane and in the cytoplasm except within cell organelles of the perikaryon, dendrites, axon, and axon terminals. The nucleus was also stained but less heavily, and the nucleoli remained unstained. Synaptic vesicles in the axon terminals were densely stained. The results suggest that gamma- subspecies might be functionally involved in modulation of nuclear function and of pre- and postsynaptic functions including transmitter release in the rat Purkinje cells.
DOI:
10.1016/s0006-291x(87)80523-5
发表时间:
1987
影响因子:
3.1
作者:
Kraft,AS;Appling,C;Berkow,RL
通讯作者:
Berkow,RL
DOI:
10.1073/pnas.83.11.4053
发表时间:
1986
影响因子:
11.1
作者:
Worley,PF;Baraban,JM;DeSouza,EB;Snyder,SH
通讯作者:
Snyder,SH
DOI:
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发表时间:
1987
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Philippe,J;Drucker,DJ;Habener,JF
通讯作者:
Habener,JF