Different compartments of apical CA1 dendrites have different plasticity thresholds for expressing synaptic tagging and capture.
Different compartments of apical CA1 dendrites have different plasticity thresholds for expressing synaptic tagging and capture.
复制标题
顶端 CA1 树突的不同区室具有不同的表达突触标记和捕获的可塑性阈值
DOI:
10.1101/lm.2095811
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发表时间:
2011
影响因子:
2
通讯作者:
Sajikumar
中科院分区:
文献类型:
--
作者:
Sajikumar
The consolidation process from short- to long-term memory depends on the type of stimulation received from a specific neuronal network and on the cooperativity and associativity between different synaptic inputs converging onto a specific neuron. We show here that the plasticity thresholds for inducing LTP are different in proximal and distal compartments of apical dendrites. In addition, we show interactions between the proximal and distal compartments of the apical dendrites by providing evidence that even a subthreshold stimulus can activate plasticity-related proteins, such as PKMζ, enabling associativity between two distinct dendritic compartments in apical dendrites to occur.
DOI:
10.1073/pnas.1016849108
发表时间:
2011-02-08
影响因子:
11.1
作者:
Sajikumar, Sreedharan;Korte, Martin
通讯作者:
Korte, Martin
影响因子:
3.5
作者:
M. Witter
通讯作者:
M. Witter
影响因子:
5.3
作者:
Sheeja Navakkode;Sreedharan Sajikumar;J. Frey
通讯作者:
J. Frey