Plasma membrane estrogen receptors.
Plasma membrane estrogen receptors.
复制标题
DOI：
10.1016/j.tem.2009.06.009
复制
发表时间：
2009-12
影响因子：
10.9
通讯作者：
Levin, Ellis R.
中科院分区：
文献类型：
--
作者：
Levin, Ellis R.
It is now firmly established that estrogen and all sex steroid receptors exist in discrete cellular pools outside the nucleus. Estrogen receptors (ER) have been localized to the plasma membrane where both ERα and ERβ function in a wide variety of cells and organs. ERs have also been found in discrete cytoplasmic organelles including mitochondria and the endoplasmic reticulum. In ligand-dependent fashion, each ER pool contributes to the overall, integrated effects of estrogens producing biological outcomes. This review highlights the recent work establishing new roles and targets of membrane ER signaling. Such actions include prevention of vascular injury or cardiac hypertrophy, sexual behavior and pain perception mediated through the central nervous system, osteoblast survival, and fluid resorption in the colon.
登录
查看更多内容
影响因子：
64.8
作者：
PIETRAS, RJ;SZEGO, CM
通讯作者：
SZEGO, CM
影响因子：
3.3
作者：
Acconcia, F;Ascenzi, P;Marino, M
通讯作者：
Marino, M
影响因子：
16
作者：
Le Romancer, Muriel;Treilleux, Isabelle;Corbo, Laura
通讯作者：
Corbo, Laura
影响因子：
4.8
作者：
Pedram, Ali;Razandi, Mahnaz;Levin, Ellis R.
通讯作者：
Levin, Ellis R.
影响因子：
4.8
作者：
Aguirre, J. Ignacio;Plotkin, Lilian I.;Bellido, Teresita
通讯作者：
Bellido, Teresita