Conductive 3D nano-biohybrid systems based on densified carbon nanotube forests and living cells.
Conductive 3D nano-biohybrid systems based on densified carbon nanotube forests and living cells.
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DOI：
10.1557/s43578-023-01163-x
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发表时间：
2024
影响因子：
2.7
通讯作者：
Abadi, Parisa Pour Shahid Saeed
中科院分区：
文献类型：
--
作者：
Bagheri, Roya;Ball, Alicia K.;Kasraie, Masoud;Chandra, Aparna;Chen, Xinqian;Miskioglu, Ibrahim;Shan, Zhiying;Abadi, Parisa Pour Shahid Saeed
关键词：
导电生物混合细胞材料系统在生物电子学和生物机器人学中有应用。迄今为止，导电支架仅限于具有低电导率或2D片材的那些。在这里，使用与碳纳米管（CNT）森林集成的成纤维细胞或心肌细胞开发了3D生物混合导电系统，所述碳纳米管森林由于与明胶涂层的相互作用而致密化。开发了高度范围为120-240 µm且平均电导率为0.6 S/cm的CNT森林支架，并显示其具有细胞相容性，如在第1天通过两种细胞的活-死测定测量的大于89%的活力所证明的。细胞在CNT森林支架的顶部和沿着高度扩散。最后，支架对与心肌细胞成熟和功能相关的基因表达或成纤维细胞迁移、粘附和扩散没有不利影响。结果表明，该支架可用于从器官芯片系统到肌肉致动器的应用。
Conductive biohybrid cell-material systems have applications in bioelectronics and biorobotics. To date, conductive scaffolds are limited to those with low electrical conductivity or 2D sheets. Here, 3D biohybrid conductive systems are developed using fibroblasts or cardiomyocytes integrated with carbon nanotube (CNT) forests that are densified due to interactions with a gelatin coating. CNT forest scaffolds with a height range of 120–240 µm and an average electrical conductivity of 0.6 S/cm are developed and shown to be cytocompatible as evidenced from greater than 89% viability measured by live-dead assay on both cells on day 1. The cells spread on top and along the height of the CNT forest scaffolds. Finally, the scaffolds have no adverse effects on the expression of genes related to cardiomyocyte maturation and functionality, or fibroblast migration, adhesion, and spreading. The results show that the scaffold could be used in applications ranging from organ-on-a-chip systems to muscle actuators.
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DOI：
10.1126/science.abh0474
发表时间：
2022-02-11
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Lee KY;Park SJ;Matthews DG;Kim SL;Marquez CA;Zimmerman JF;Ardoña HAM;Kleber AG;Lauder GV;Parker KK
通讯作者：
Parker KK
影响因子：
3.9
作者：
Kavoosi, Gholamreza;Dadfar, Seyed Mohammad Mahdi;Dadfar, Seyed Mohammad Ali;Ahmadi, Farhad;Niakosari, Mehrdad
通讯作者：
Niakosari, Mehrdad
DOI：
10.3390/s18051368
发表时间：
2018-04-27
期刊：
Sensors (Basel, Switzerland)
影响因子：
--
作者：
Li YT;Tian Y;Tian H;Tu T;Gou GY;Wang Q;Qiao YC;Yang Y;Ren TL
通讯作者：
Ren TL
DOI：
10.1115/1.4035622
发表时间：
2017-07-01
影响因子：
1.2
作者：
Abadi, Parisa Pour Shahid Saeed;Maschmann, Matthew R.;Cola, Baratunde A.
通讯作者：
Cola, Baratunde A.
DOI：
10.34133/2022/9824057
发表时间：
2022
期刊：
Cyborg and bionic systems (Washington, D.C.)
影响因子：
--
作者：
通讯作者：
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