Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake.
Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake.
复制标题
与口服双膦酸盐用途：正确指导用药和摄入的重要性相关的严重口腔粘膜溃疡。
DOI：
10.1155/2021/6620489
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发表时间：
2021
影响因子：
0.8
通讯作者：
Zeng W
中科院分区：
文献类型：
--
作者：
Chandran M;Zeng W
口服双膦酸盐被批准用于治疗与包括绝经后骨质疏松症在内的几种疾病相关的骨丢失。虽然一般耐受性良好，但可能发生胃食管反流和食管及消化性溃疡等不良反应。口腔粘膜炎和溃疡是鲜为人知的副作用。适当的咨询和严格遵守行政指示至关重要。我们描述了一例老年女性双磷酸盐诱导的严重口腔粘膜溃疡病例，该病例是由错误的说明和/或对口服阿仑膦酸钠摄入说明的错误理解引起的。
Oral bisphosphonates are approved for the treatment of bone loss associated with several conditions including postmenopausal osteoporosis. Although generally well tolerated, adverse effects such as gastroesophageal reflux and oesophageal and peptic ulceration may occur. Oral mucositis and ulceration are lesser-known side effects. Proper counselling and rigorous adherence to the administration instructions are crucial. We describe a case of bisphosphonate-induced severe oral mucosal ulceration in an elderly woman that was caused by incorrect instructions and/or incorrect understanding of instructions for oral alendronate intake.
影响因子：
3.3
作者：
Gonzalez-Moles, MA;Bagan-Sebastian, JV
通讯作者：
Bagan-Sebastian, JV