Reversibility of cognitive disorder after treatment of dural arteriovenous fistulae
Reversibility of cognitive disorder after treatment of dural arteriovenous fistulae
复制标题
硬脑膜动静脉瘘治疗后认知障碍的可逆性
DOI：
10.1007/s00234-009-0567-y
复制
发表时间：
2009
期刊：
影响因子：
2.8
通讯作者：
Y. Yoshii
中科院分区：
文献类型：
--
作者：
Y. Kai;Koichi Ito;T. Kinjo;Youhei Hokama;H. Nagamine;S. Kushi;S. Kinjo;Yukihiro Tsuchida;K. Sugimoto;M. Morioka;S. Yano;Yuki Ohmori;T. Kawano;Hideo Nakamura;K. Makino;J. Hamada;J. Kuratsu;Y. Yoshii
IntroductionDural arteriovenous fistulae (DAVF) occasionally lead to cognitive disorders whose reversibility after DAVF treatment remains unclear. We studied changes on pre- and post-treatment magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) scans in ten patients with cognitive disorder due to DAVF.MethodsWe studied the symptoms, pre- and post-treatment MRI scans, SPECT findings, and mini-mental state examination (MMSE) and treatment results in ten patients with cognitive disorder due to DAVF. They were divided into two groups; the post-treatment MMSE score exceeded 25 points in group 1 (n = 6) and was lower than 24 points in group 2 (n = 4).ResultsIn the six group 1 patients, pretreatment diffusion-weighted images (DWI) showed hyperintense areas, and SPECT scans demonstrated the preservation of vasoreactivity after acetazolamide challenge. In the four group 2 patients, pretreatment SPECT demonstrated hypoperfusion areas that coincided with the hyperintense areas seen on DWI; there were areas with marked disturbance in vasoreactivity. The post-treatment MMSE score in groups 1 and 2 improved by 13.7 ± 2.4 and 3.8 ± 1.0 points, respectively; the difference was significant at p < 0.01.ConclusionIn patients with cognitive disorder due to DAVF, the preservation of vasoreactivity on SPECT after acetazolamide challenge indicates that their cognitive disorder may be reversible by DAVF treatment.
DOI：
10.1001/jama.1993.03500180078038
发表时间：
1993-05
期刊：
JAMA
影响因子：
--
作者：
R. Crum;J. Anthony;S. Bassett;M. Folstein
通讯作者：
R. Crum;J. Anthony;S. Bassett;M. Folstein
影响因子：
4.1
作者：
SUNDT, TM;PIEPGRAS, DG
通讯作者：
PIEPGRAS, DG