Responses of auditory nerve fibers of the unanesthetized decerebrate cat to click pairs as simulated echoes.
Responses of auditory nerve fibers of the unanesthetized decerebrate cat to click pairs as simulated echoes.
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未麻醉的去大脑猫的听觉神经纤维对作为模拟回声的点击对的反应。
DOI：
10.1152/jn.1996.76.1.17
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Kim,DO
中科院分区：
文献类型：
--
作者：
Parham,K;Zhao,HB;Kim,DO
1.为了阐明周边的贡献，在听觉系统中的“回声”处理，我们研究了听神经反应的特点，点击对刺激在未麻醉，去大脑猫。我们使用了峰值水平为45，65和85 dB SPL re 20 microPa的等电平点击对。的interclick间隔范围从1到32毫秒。这项研究报告的结果，从78个听觉神经纤维在7只猫。将纤维分为2组：33个低自发频率（SR）和45个高自发频率（SR），SR分别小于和>或= 20 spikes/s。介绍了一种方法来量化的第二次点击响应，其恢复作为一个功能的interclick间隔。2.一般情况下，听神经纤维表现出逐渐恢复的第二次点击反应的interclick间隔增加。第二次点击反应的恢复功能中出现的纤维种群之间的SR的显着差异。低SR纤维的第二次点击反应的恢复功能的点击水平从45分贝SPL增加到85分贝SPL的变化不大。相比之下，高SR纤维表现出较慢的恢复与增加点击水平从45到85分贝SPL。在45和65 dB SPL时，两个SR组的恢复功能相似。在85 dB SPL时，高SR光纤比低SR光纤表现出更慢的恢复，而与光纤特征频率无关。在低SR纤维中，50%第二次点击反应的interclick间期范围为1至6 ms（平均1.4 ms）。高SR纤维在50%第二次点击反应时的互点击间隔，而与低SR纤维在45和65 dB SPL时的互点击间隔相似，高SR纤维在85 dB SPL时的范围为2至16 ms（平均3 ms）。3.我们还研究了听觉神经复合动作电位（CAP）诱发的点击对刺激的各种interclick间隔和点击水平。随着叩击间隔的增加，二次叩击CAP的振幅增加，随着叩击强度的增加，二次叩击CAP的恢复速度减慢。在45 dB SPL时，第二次点击CAP的恢复功能与高SR和低SR纤维的恢复功能相似。在较高水平，CAP表现出较低的第二次点击反应值比高和低SR纤维人群的interclick间期< 4-8 ms。在85 dB SPL，随着interclick间期增加，在8和16 ms之间，CAP第二次点击反应收敛于高SR纤维，到32 ms，CAP，高和低SR纤维的第二次点击反应值相似。4.目前的结果是一致的，在听觉神经水平的前掩蔽研究，都表明短期减少的神经反应。然而，这两个结果的不同之处在于，我们观察到，高SR纤维表现出较慢的恢复比低SR纤维在响应点击对刺激，相反的趋势中观察到的纯音突发的反应的前掩蔽研究。5.本研究结果为比较听神经元对类似刺激的反应提供了参考。这些信息应该有助于阐明听觉系统中回声处理的周边贡献。
1. To elucidate the peripheral contribution to "echo" processing in the auditory system, we examined the characteristics of auditory nerve responses to click-pair stimuli in unanesthetized, decerebrate cats. We used equilevel click pairs at peak levels of 45, 65, and 85 dB SPL re 20 microPa. The interclick intervals ranged from 1 to 32 ms. This study reports results from 78 auditory nerve fibers in 7 cats. The fibers were divided into 2 groups: 33 low- and 45 high-spontaneous rate (SR), with SRs less than and > or = 20 spikes/s, respectively. A method was introduced to quantify the second-click response, and its recovery was examined as a function of the interclick interval. 2. In general, auditory nerve fibers showed a gradual recovery of the second-click response as interclick interval was increased. Noticeable differences in the second-click response recovery functions emerged among fiber populations that were related to the SR. Low-SR fibers showed little change in the recovery functions of the second-click response as the click level was increased from 45 to 85 dB SPL. In contrast, high-SR fibers showed slower recoveries with increasing click level from 45 to 85 dB SPL. At 45 and 65 dB SPL, the recovery functions of the two SR groups were similar. At 85 dB SPL, high-SR fibers exhibited slower recovery than low-SR fibers, regardless of fiber characteristic frequency. The interclick intervals at 50% second-click response ranged from 1 to 6 ms (mean, 1.4 ms) among low-SR fibers. The interclick intervals at 50% second-click response for high-SR fibers, whereas similar to those for the low-SR fibers at 45 and 65 dB SPL, ranged from 2 to 16 ms (mean, 3 ms) for high-SR fibers, at 85 dB SPL. 3. We also examined auditory nerve compound action potentials (CAPs) evoked by click-pair stimuli for various interclick intervals and click levels. With increasing interclick interval, the amplitude of the second-click CAP increased, and with increasing level, the second-click CAP showed slower recovery. At 45 dB SPL, the recovery functions of the second-click CAP were similar to those of the high- and low-SR fibers. At higher levels, the CAP exhibited lower second-click response values than both high- and low-SR fiber populations for interclick intervals < 4-8 ms. At 85 dB SPL, as interclick interval increased, between 8 and 16 ms, the CAP second-click response converged with that of the high-SR fibers, and by 32 ms, the second-click response values were similar for the CAP, high- and low-SR fibers. 4. The present results are consistent with those of forward masking studies at the level of the auditory nerve in that both demonstrate a short-term reduction of the neural responses. However, the two results differ in that we observed that high-SR fibers exhibited slower recovery than low-SR fibers in response to click-pair stimuli, opposite of the trend observed in the forward masking studies of responses to pure-tone bursts. 5. The present results on auditory nerve fiber responses to click-pair stimuli provide a reference for comparison with responses of central auditory neurons to similar stimuli. This information should serve to elucidate the peripheral contribution to the processing of echoes in the auditory system.
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影响因子：
2.4
作者：
GOBLICK, TJ;PFEIFFER, RR
通讯作者：
PFEIFFER, RR
咔嗒声与咔嗒声对的双耳交互
DOI：
--
发表时间：
1962
期刊：
影响因子：
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作者：
Gerald G. Harris;J. Flanagan;B. Watson
通讯作者：
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影响因子：
56.9
作者：
LIBERMAN, MC
通讯作者：
LIBERMAN, MC
通过两间隔强制选择程序测量听觉神经中的探测音阈值。
DOI：
10.1121/1.395159
发表时间：
1987
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
Relkin,EM;Pelli,DG
通讯作者：
Pelli,DG
DOI：
--
发表时间：
1964
期刊：
影响因子：
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作者：
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通讯作者：
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