Prevalence of and risk factors for curable sexually transmitted infections on Bubaque Island, Guinea Bissau.
Prevalence of and risk factors for curable sexually transmitted infections on Bubaque Island, Guinea Bissau.
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DOI：
10.1136/sextrans-2019-054351
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发表时间：
2021-03
影响因子：
3.6
通讯作者：
Last A
中科院分区：
文献类型：
--
作者：
Cowley G;Milne G;Teixeira da Silva E;Nakutum J;Rodrigues A;Vasileva H;Mabey D;Versteeg B;Last A
性传播感染的并发症可导致严重的发病率和死亡率。迄今为止，尚未在几内亚比绍比亚戈斯群岛进行任何性传播感染人群研究。我们的目标是评估沙眼衣原体(Ct)、淋病奈瑟菌(Ng)、生殖支原体(Mg)、阴道毛滴虫(TV)和梅毒螺旋体(Tp)在人口最多的岛屿Bubaque的流行情况和危险因素。在布巴克岛对16至49岁的人进行了一项横断面调查。参与者被要求回答一份关于性传播感染危险因素的问卷，提供尿样(男性和女性)和阴道拭子(女性)进行Ct、Ng、Mg和TV的聚合酶链式反应检测，并提供干血点进行TP颗粒凝集试验。对数据进行分析以估计性传播感染的患病率，并使用Logistic回归分析确定危险因素。总体而言，14.9%的参与者被发现患有可治愈的性传播感染，其中电视的患病率最高(5.9%)，其次是CT(3.8%)、Ng(3.8%)、MG(1.9%)和TP(0.8%)。有任何性传播感染的重要风险因素包括女性、年轻和同时有伴侣关系。既往有过最佳治疗的性传播感染是一个保护性因素。这项研究表明，比亚戈斯群岛存在相当大的性传播感染负担，强调需要进行诊断性检测，以便及早发现和治疗这些病原体，以阻止目前的传播。此外，这些结果表明，需要对比亚戈斯群岛的性传播感染负担进行进一步研究，以帮助提供信息并制定国家性传播感染控制战略。
Complications from sexually transmitted infections (STIs) can result in severe morbidity and mortality. To date, no STI population studies have been conducted on the Bijagos Islands, Guinea Bissau. Our objective was to estimate the prevalence of and identify risk factors for Chlamydia trachomatis (Ct), Neisseria gonorrhoea (Ng), Mycoplasma genitalium (Mg), Trichomonas vaginalis (Tv) and Treponema pallidum (Tp) on Bubaque, the most populated island. A cross-sectional survey was conducted on the island of Bubaque among people aged 16–49 years. Participants were asked to answer a questionnaire on STI risk factors, to provide urine samples (men and women) and vaginal swabs (women) for PCR testing for Ct, Ng, Mg and Tv, and to provide dry blood spots for Tp particle agglutination assays. Data were analysed to estimate the prevalence of STIs and logistic regression was used to identify risk factors. In total, 14.9% of participants were found to have a curable STI, with the highest prevalence being observed for Tv (5.9%) followed by Ct (3.8%), Ng (3.8%), Mg (1.9%) and Tp (0.8%). Significant risk factors for having any STI included being female, younger age and concurrent partnership. Having had a previous STI that was optimally treated was a protective factor. This study demonstrates that there is a considerable burden of STI on the Bijagos Islands, stressing the need for diagnostic testing to facilitate early detection and treatment of these pathogens to stop ongoing transmission. Moreover, these results indicate the need to conduct further research into the STI burden on the Bijagos Islands to help inform and develop a national STI control strategy.
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影响因子：
3.2
作者：
Last, Anna R.;Burr, Sarah E.;Bailey, Robin L.
通讯作者：
Bailey, Robin L.
影响因子：
3.6
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作者：
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