Use of 3D printers to create a patient-specific 3D bolus for external beam therapy.
Use of 3D printers to create a patient-specific 3D bolus for external beam therapy.
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DOI：
10.1120/jacmp.v16i3.5247
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发表时间：
2015-05-08
影响因子：
2.1
通讯作者：
Xu Z
中科院分区：
文献类型：
--
作者：
Burleson S;Baker J;Hsia AT;Xu Z
这篇论文的目的是证明一种廉价的3D打印机可以用来制造用于外照射治疗的患者特定的丸剂，并展示我们可以在我们的治疗计划系统中准确地对打印的丸剂进行建模，以便准确地提供治疗。通过深度剂量百分比测量和组织最大比测量，确定了物理密度为1.04的丙烯腈-丁二烯-苯乙烯和聚乳酸作为丸剂材料的特性，以及电子密度为和的特性。使用Gafchroic EBT2胶片和Rando体模进行剂量平面比较，以验证治疗计划的准确性。我们在Eclipse治疗计划系统中准确地对一种打印材料建模，为其分配了260的Hounsfield单位。我们还能够使用伽玛分析进行剂量平面比较来验证准确的治疗计划。剂量差为5%、DTA为2 mm的伽玛标准，合格率为86.5%；剂量差为5%、DTA为3 mm的伽马标准，合格率为95%。我们能够使用廉价的3D打印机创建针对患者的丸剂，并在我们的治疗计划系统中对其进行建模，以实现准确的治疗交付。PAC编号：87.53 Jw，87.53 Kn，87.56 ng
The purpose of this paper is to demonstrate that an inexpensive 3D printer can be used to manufacture patient‐specific bolus for external beam therapy, and to show we can accurately model this printed bolus in our treatment planning system for accurate treatment delivery. Percent depth‐dose measurements and tissue maximum ratios were used to determine the characteristics of the printing materials, acrylonitrile butadiene styrene and polylactic acid, as bolus material with physical density of 1.04 and , and electron density of and , respectively. Dose plane comparisons using Gafchromic EBT2 film and the RANDO phantom were used to verify accurate treatment planning. We accurately modeled a printing material in Eclipse treatment planning system, assigning it a Hounsfield unit of 260. We were also able to verify accurate treatment planning using gamma analysis for dose plane comparisons. With gamma criteria of 5% dose difference and 2 mm DTA, we were able to have 86.5% points passing, and with gamma criteria of 5% dose difference and 3 mm DTA, we were able to have 95% points passing. We were able to create a patient‐specific bolus using an inexpensive 3D printer and model it in our treatment planning system for accurate treatment delivery. PACS numbers: 87.53.Jw, 87.53.Kn, 87.56.ng
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