Genetic and cytogenetic localisation of the homeo box containing genes on mouse chromosome 6 and human chromosome 7.
Genetic and cytogenetic localisation of the homeo box containing genes on mouse chromosome 6 and human chromosome 7.
复制标题
含有小鼠 6 号染色体和人类 7 号染色体上基因的同源盒的遗传和细胞遗传学定位。
DOI:
10.1002/j.1460-2075.1986.tb04585.x
复制
发表时间:
1986
期刊:
影响因子:
--
通讯作者:
Lehrach,H
中科院分区:
文献类型:
--
作者:
Bućan,M;Yang-Feng,T;Colberg-Poley,AM;Wolgemuth,DJ;Guenet,JL;Francke,U;Lehrach,H
Probes from the m6 homeo box cluster were mapped to mouse chromosome 6 by somatic cell genetics, in situ hybridisation, and by a Mus spretus‐‐Mus musculus backcross mapping system. In addition, the testis‐specific homeo box containing cDNA, clone, HBT‐1, has been mapped using the same back‐cross system and the B X D recombinant inbred strain set. Close genetic and physical linkage between the m6 cluster and HBT‐1 was demonstrated, positioning these sequences to the same local cluster of homeo box containing genes. The map location of this cluster between IgK and Tcrb coincides with the morphological mutation hypodactyly (Hd). Synteny has been observed between a region of mouse chromosome 6 and the long arm of human chromosome 7 encompassing the markers Cpa, Tcrb and Try‐1. Here we localise human sequences hybridising to the mouse m6 probes to the short arm of chromosome 7, breaking the region of synteny.
DOI:
--
发表时间:
1978
期刊:
Cytogenetics and Cell Genetics
影响因子:
--
作者:
N. Oliver;U. Francke
通讯作者:
U. Francke
DOI:
--
发表时间:
1983
期刊:
Somatic Cell Genetics
影响因子:
--
作者:
S. Pearson;P. Tetri;Donna L. George;Uta Francke
通讯作者:
Uta Francke