Control of metabolism: where is the theory?
Control of metabolism: where is the theory?
复制标题
新陈代谢的控制：理论在哪里？
DOI：
10.1016/0968-0004(87)90108-3
复制
发表时间：
1987
影响因子：
13.8
通讯作者：
M. Savageau
中科院分区：
文献类型：
--
作者：
M. Savageau
尽管有人建议我们不应该开始建立一个包含特殊假设或先验集合的代数模型‘，但S和卡塞尔在他们最近的TIBS项目中所做的恰恰是他们的许多假设是有问题的，其他人与该领域的现有知识不符，关于控制分析方法中嵌入的不足之处以及随之而来的混乱超出了简短说明的范围，我将仅考虑从Kacser和Porteous论文中摘取的几个例子，这些假设是错误的逻辑上的不一致和错误的结论这些缺点表明，他们所提倡的方法不适合作为该领域的理论基础
In spite of their admomshmg others' we should not start to set up an algebraic model incorporating ad hoc assumptions or a priori assemons', tins~ s exactly what Kacser and Porteous have done m their recent TIBS amcle m Many of their assumpuons are of quesuonable vah&ty, others are at odds with current knowledge in the field Full documentauon of the inadequacies embedded Wltinn the% ontrol analym'approach and of the confusion that has followed its mtrodnctlon is beyond the scope of a short note In what follows, I shall hmlt consideration to just a few examples taken from the Kacser and Porteous paper that dlustrate faulty assumptions, Iogtcal inconsistencies and mistaken conclusions These shortcomangs demonstrate that the approach they are promoting is inappropriate as a theoretical foundauon for the field
影响因子：
56.9
作者：
SRIVASTAVA, DK;BERNHARD, SA
通讯作者：
BERNHARD, SA