The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013.
The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013.
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DOI：
10.1093/nar/gks1146
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发表时间：
2013-01
影响因子：
14.9
通讯作者：
Steinbeck C
中科院分区：
文献类型：
--
作者：
Hastings J;de Matos P;Dekker A;Ennis M;Harsha B;Kale N;Muthukrishnan V;Owen G;Turner S;Williams M;Steinbeck C
Chebi（http://www.ebi.ac.uk/chebi）是一个生物学兴趣的化学实体的数据库和本体，Chebi在内容上继续静静地增长，并增加了一些新功能。除了纳入所有用户要求的化合物外，我们的注释工作还具有紧急免疫学，天然产品和代谢物，在许多物种中都被分类为“ IS_A”化学物质可用于利用分类层次结构的语义推理工具。涉及基因本体论的过程（GO），并且由于这项努力，GO中的大多数涉及化学涉及化学涉及过程参与其中的Chebi实体都必须纳入许多与生物学相关的化合物。最值得注意的是提供动态新的基于图形的本体本体可视化。
ChEBI (http://www.ebi.ac.uk/chebi) is a database and ontology of chemical entities of biological interest. Over the past few years, ChEBI has continued to grow steadily in content, and has added several new features. In addition to incorporating all user-requested compounds, our annotation efforts have emphasized immunology, natural products and metabolites in many species. All database entries are now ‘is_a’ classified within the ontology, meaning that all of the chemicals are available to semantic reasoning tools that harness the classification hierarchy. We have completely aligned the ontology with the Open Biomedical Ontologies (OBO) Foundry-recommended upper level Basic Formal Ontology. Furthermore, we have aligned our chemical classification with the classification of chemical-involving processes in the Gene Ontology (GO), and as a result of this effort, the majority of chemical-involving processes in GO are now defined in terms of the ChEBI entities that participate in them. This effort necessitated incorporating many additional biologically relevant compounds. We have incorporated additional data types including reference citations, and the species and component for metabolites. Finally, our website and web services have had several enhancements, most notably the provision of a dynamic new interactive graph-based ontology visualization.
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影响因子：
14.9
作者：
Wishart DS;Knox C;Guo AC;Eisner R;Young N;Gautam B;Hau DD;Psychogios N;Dong E;Bouatra S;Mandal R;Sinelnikov I;Xia J;Jia L;Cruz JA;Lim E;Sobsey CA;Shrivastava S;Huang P;Liu P;Fang L;Peng J;Fradette R;Cheng D;Tzur D;Clements M;Lewis A;De Souza A;Zuniga A;Dawe M;Xiong Y;Clive D;Greiner R;Nazyrova A;Shaykhutdinov R;Li L;Vogel HJ;Forsythe I
通讯作者：
Forsythe I
基因本体论：2011年的增强。
影响因子：
14.9
作者：
Gene Ontology Consortium
通讯作者：
Gene Ontology Consortium
影响因子：
4.3
作者：
Ferreira, Joao D.;Couto, Francisco M.
通讯作者：
Couto, Francisco M.
影响因子：
5.8
作者：
Hoehndorf, Robert;Dumontier, Michel;Gkoutos, Georgios V.
通讯作者：
Gkoutos, Georgios V.
影响因子：
14.9
作者：
Alcántara R;Axelsen KB;Morgat A;Belda E;Coudert E;Bridge A;Cao H;de Matos P;Ennis M;Turner S;Owen G;Bougueleret L;Xenarios I;Steinbeck C
通讯作者：
Steinbeck C