Transcranial direct current stimulation modulates implicit attitudes towards food in eating disorders.
Transcranial direct current stimulation modulates implicit attitudes towards food in eating disorders.
复制标题
经颅直流电刺激调节饮食失调患者对食物的内隐态度。
DOI：
10.1002/eat.23046
复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
C. Papagno
中科院分区：
文献类型：
--
作者：
G. Mattavelli;A. Gallucci;G. Schiena;A. D’Agostino;T. Sassetti;S. Bonora;S. Bertelli;A. Benetti;E. Tugnoli;G. Ruggiero;S. Sassaroli;L. R. Romero Lauro;O. Gambini;C. Papagno
客观化
参与食品加工的区域的神经调节越来越多地被用于饮食行为的研究，但结果存在争议。我们评估了阳极经颅直流电刺激(a-tdcs)对进食障碍(EDS)患者食物和身体隐性偏好的影响。
方法
36名ED患者和36名健康女性完成了三个疗程，分别在内侧前额叶皮质(MPFC)、右侧纹状体外体区(REBA)或假手术模式下应用a-tDCs。然后，每个参与者完成了三个内隐联想测试(IATS)，分别是美味/无味的食物、体重过轻/超重的身体形象、鲜花与昆虫作为对照。计算不一致区块与一致区块之间的潜伏期差异(D评分)。
结果
小组交互作用的tdcs对IAT-Food D评分有重要意义，在假手术中，患者对美味食物的偏好比对照组更弱，但a-tdcs会议没有。特别是，与假刺激相比，REBA刺激显著增加了患者的D分数。此外，与mPFC和REBA相比，a-tDCs选择性地增加了患者在IAT-食物不协调块中的反应时间。
讨论
额叶和枕叶皮质的A-tDCs调节ED患者的食物偏好。这种影响是针对食物图像的，在患者中是有选择性的，但在健康参与者中不是。这些发现表明，这些区域的神经调节可能会影响内隐的食物态度。
OBJECTIVE
Neuromodulation of regions involved in food processing is increasingly used in studies on eating behaviors, but results are controversial. We assessed the effects of anodal transcranial direct current stimulation (a-tDCS) on food and body implicit preferences in patients with eating disorders (EDs).
METHOD
Thirty-six ED patients and 36 healthy females completed three sessions with a-tDCS applied to the medial-prefrontal cortex (mPFC), the right extrastriate body area (rEBA) or in sham mode. Each participant then completed three Implicit Association Tests (IATs) on tasty/tasteless food, underweight/overweight body images, flowers versus insects as control. Differences in latency between incongruent and congruent blocks were calculated (D score).
RESULTS
The tDCS by group interaction was significant for the IAT-food D score, with patients showing weaker preference for tasty food than controls in sham, but not a-tDCS sessions. In particular, rEBA stimulation significantly increased patients' D score compared to sham. Moreover, a-tDCS over mPFC and rEBA selectively increased patients' reaction times in the incongruent blocks of the IAT-food.
DISCUSSION
A-tDCS on frontal and occipito-temporal cortices modulated food preferences in ED patients. The effect was specific for food images and selective in patients, but not in healthy participants. These findings suggest that neuromodulation of these regions could affect implicit food attitudes.
影响因子：
7.6
作者：
Greenwald, AG;Nosek, BA;Banaji, MR
通讯作者：
Banaji, MR
影响因子：
7.6
作者：
Greenwald, AG;McGhee, DE;Schwartz, JLK
通讯作者：
Schwartz, JLK